Cancer proteogenomics integrates genomics, transcriptomics and mass spectrometry (MS)-based
proteomics to gain insights into cancer biology and treatment efficacy. A …

The extracellular matrix (ECM) is a fundamental component of multicellular organisms that
provides mechanical and chemical cues that orchestrate cellular and tissue organization and …

Microscopic thin section images are a major source of information on physical properties,
crystallization processes, and the evolution of rocks. Extracting the boundaries of grains is of …

The heat stored in the Earth provides the energy which drives the thermal convection caused
by thermal buoyancy in the Earth’s liquid outer core and plastic mantle. It is thus one of the …

We describe the impact of advances in mass measurement accuracy, ±10 ppm (internally
calibrated), on protein identification experiments. This capability was brought about by delayed …

Human growth hormone (hGH) forms a 1:2 complex with the extracellular domain of its
receptor-binding protein (hGHbp) as studied by crystallization, size exclusion chromatography, …

Mitochondria are complex organelles that house essential pathways involved in energy
metabolism, ion homeostasis, signalling and apoptosis. To understand mitochondrial pathways …

It is generally recognized that the temperature profile in a borehole is influenced by both
groundwater flow and past climatic change. Geophysicists seek to remove such effects from a …

We report a general mass spectrometric approach for the rapid identification and characterization
of proteins isolated by preparative two-dimensional polyacrylamide gel electrophoresis…

… The thermal cycling parameters for the PCR were as follows: 95 C for 5 min, followed by
45 cycles of 95 C for 10 sec, 49 C for 7 sec, and 72 C for 25 sec. The relative mRNA quantity …