Background Perforated necrotizing enterocolitis is a major cause of morbidity and mortality
in premature infants, and the optimal treatment is uncertain. We designed this multicenter …

Hepatocellular carcinoma (HCC) is the third cancer killer worldwide with >600,000 deaths
every year. Although the major risk factors are known, therapeutic options in patients remain …

Background As a high-prevalence health condition, hypertension is clinically costly, difficult
to manage, and often leads to severe and life-threatening diseases such as cardiovascular …

Background & Aims: Oval cells are postnatal hepatic progenitors with high proliferative potential
and bipotent differentiation ability to become hepatocytes and cholangiocytes. Because …

Regenerative medicine and emerging biotechnologies stand to revolutionize the practice of
medicine. Advancements in stem cell biology, including embryonic and postnatal somatic …

The early-gestation fetus heals incisional skin wounds rapidly and scarlessly. The morphology
with which the fetus heals excisional skin wounds remains unclear. To characterize …

Numerous liver diseases are associated with extensive oxidative tissue damage. It is well
established that Wnt/β-catenin signaling directs multiple hepatocellular processes, including …

The increased expression of SIRT1 has recently been identified in numerous human tumors
and a possible correlation with c-Myc oncogene has been proposed. However, it remains …

BACKGROUND & AIMS: Ischemia and reperfusion injury are common causes of oxidative
tissue damage associated with many liver diseases and hepatic surgery. The Wnt–β-catenin …

PURPOSE: The authors report their experience with doxycycline sclerotherapy as primary
treatment of head and neck lymphatic malformations (LMs) in children. METHODS: A …