User profiles for Karl Kumbier
Karl KumbierUniversity of California San Francisco Verified email at berkeley.edu Cited by 2494 |
Definitions, methods, and applications in interpretable machine learning
Machine-learning models have demonstrated great success in learning complex patterns
that enable them to make predictions about unobserved data. In addition to using models for …
that enable them to make predictions about unobserved data. In addition to using models for …
Interpretable machine learning: definitions, methods, and applications
Machine-learning models have demonstrated great success in learning complex patterns
that enable them to make predictions about unobserved data. In addition to using models for …
that enable them to make predictions about unobserved data. In addition to using models for …
Iterative random forests to discover predictive and stable high-order interactions
Genomics has revolutionized biology, enabling the interrogation of whole transcriptomes,
genome-wide binding sites for proteins, and many other molecular processes. However, …
genome-wide binding sites for proteins, and many other molecular processes. However, …
[PDF][PDF] Curating a COVID-19 data repository and forecasting county-level death counts in the United States
As the COVID-19 outbreak evolves, accurate forecasting continues to play an extremely
important role in informing policy decisions. In this article, we present our continuous curation of …
important role in informing policy decisions. In this article, we present our continuous curation of …
A debiased MDI feature importance measure for random forests
Tree ensembles such as Random Forests have achieved impressive empirical success across
a wide variety of applications. To understand how these models make predictions, people …
a wide variety of applications. To understand how these models make predictions, people …
Artificial intelligence and statistics
Artificial intelligence (AI) is intrinsically data-driven. It calls for the application of statistical
concepts through human-machine collaboration during the generation of data, the …
concepts through human-machine collaboration during the generation of data, the …
[HTML][HTML] A novel random forest approach to revealing interactions and controls on chlorophyll concentration and bacterial communities during coastal phytoplankton …
Increasing occurrence of harmful algal blooms across the land–water interface poses significant
risks to coastal ecosystem structure and human health. Defining significant drivers and …
risks to coastal ecosystem structure and human health. Defining significant drivers and …
Selection of optimal cell lines for high-content phenotypic screening
High-content microscopy offers a scalable approach to screen against multiple targets in a
single pass. Prior work has focused on methods to select “optimal” cellular readouts in …
single pass. Prior work has focused on methods to select “optimal” cellular readouts in …
A scalable screening platform for phenotypic subtyping of ALS patient-derived fibroblasts
A major challenge for understanding and treating Amyotrophic Lateral Sclerosis (ALS) is that
most patients have no known genetic cause. Even within defined genetic subtypes, patients …
most patients have no known genetic cause. Even within defined genetic subtypes, patients …
Refining interaction search through signed iterative random forests
Advances in supervised learning have enabled accurate prediction in biological systems
governed by complex interactions among biomolecules. However, state-of-the-art predictive …
governed by complex interactions among biomolecules. However, state-of-the-art predictive …