Neurodegenerative diseases are among the leading causes of disability and death worldwide.
The disease-related socioeconomic burden is expected to increase with the steadily …

Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, and highly lethal lung disease
with unknown etiology and poor prognosis. IPF patients die within 2 years after diagnosis …

Background: Small cell lung cancer (SCLC) is an extremely aggressive cancer type with a
patient median survival of 6-12 months. Epidermal growth factor (EGF) signaling plays an …

The majority of the eukaryotic genome is transcribed into noncoding RNAs (ncRNAs), which
are important regulators of different nuclear processes by controlling chromatin structure. …

Complex molecular mechanisms define our responses to environmental stimuli. Beyond the
DNA sequence itself, epigenetic machinery orchestrates changes in gene expression …

In addition to nucleosomes, chromatin contains non-histone chromatin-associated proteins,
of which the high-mobility group proteins are the most abundant. Chromatin-mediated …

In healing tissue, fibroblasts differentiate to α-smooth muscle actin (SMA)-expressing
contractile-myofibroblasts, which pull the wound edges together ensuring proper tissue repair. …

Fibrosis is a condition characterized by the excessive accumulation of extracellular matrix
proteins in tissues, leading to organ dysfunction and failure. Recent studies have identified …

Lymphoid-specific helicase (LSH) is a member of the SNF2 helicase family of chromatin-remodelling
proteins. Dysfunctions or mutations in LSH causes an autosomal recessive disease …

Lung cancer (LC) is the leading cause of cancer-related deaths worldwide. On the other hand,
idiopathic pulmonary fibrosis (IPF) is the most common interstitial lung disease showing a …