User profiles for Karthickeyan C. Krishnan
 | Karthickeyan Chella KrishnanAssistant Professor, University of Cincinnati Verified email at mail.uc.edu Cited by 935 |
[HTML][HTML] Lysophospholipid acylation modulates plasma membrane lipid organization and insulin sensitivity in skeletal muscle
…, H Song, TD Green, KC Krishnan… - The Journal of …, 2021 - Am Soc Clin Investig
Aberrant lipid metabolism promotes the development of skeletal muscle insulin resistance,
but the exact identity of lipid-mediated mechanisms relevant to human obesity remains …
but the exact identity of lipid-mediated mechanisms relevant to human obesity remains …
The Lands cycle modulates plasma membrane lipid organization and insulin sensitivity in skeletal muscle
Aberrant lipid metabolism promotes the development of skeletal muscle insulin resistance,
but the exact identity of lipid-mediated mechanisms relevant to human obesity remains …
but the exact identity of lipid-mediated mechanisms relevant to human obesity remains …
Genetic architecture of heart mitochondrial proteome influencing cardiac hypertrophy
Mitochondria play an important role in both normal heart function and disease etiology. We
report analysis of common genetic variations contributing to mitochondrial and heart …
report analysis of common genetic variations contributing to mitochondrial and heart …
[HTML][HTML] Integration of multi-omics data from mouse diversity panel highlights mitochondrial dysfunction in non-alcoholic fatty liver disease
The etiology of non-alcoholic fatty liver disease (NAFLD), the most common form of chronic
liver disease, is poorly understood. To understand the causal mechanisms underlying NAFLD…
liver disease, is poorly understood. To understand the causal mechanisms underlying NAFLD…
[HTML][HTML] Sex-specific metabolic functions of adipose Lipocalin-2
KC Krishnan, S Sabir, M Shum, Y Meng… - Molecular …, 2019 - Elsevier
Objective Lipocalin-2 (LCN2) is a secreted protein involved in innate immunity and has also
been associated with several cardiometabolic traits in both mouse and human studies. …
been associated with several cardiometabolic traits in both mouse and human studies. …
[HTML][HTML] Liver pyruvate kinase promotes NAFLD/NASH in both mice and humans in a sex-specific manner
KC Krishnan, RR Floyd, S Sabir, DW Jayasekera… - Cellular and molecular …, 2021 - Elsevier
… Author links open overlay panel Karthickeyan Chella Krishnan 1 , Raquel R. Floyd 2 , … tracked
the incorporation of uniformly labeled [U- 13 C 6 ]-glucose into metabolites. Consistent with …
the incorporation of uniformly labeled [U- 13 C 6 ]-glucose into metabolites. Consistent with …
Sex differences in metabolism and cardiometabolic disorders
KC Krishnan, M Mehrabian… - Current opinion in …, 2018 - journals.lww.com
Sex differences in body fat distribution, glucose homeostasis, insulin signaling, ectopic fat
accumulation, and lipid metabolism during normal growth and in response to hormonal or …
accumulation, and lipid metabolism during normal growth and in response to hormonal or …
[PDF][PDF] Gene-by-sex interactions in mitochondrial functions and cardio-metabolic traits
…, Y Hasin-Brumshtein, L Vergnes, KC Krishnan, C Pan… - Cell metabolism, 2019 - cell.com
We studied sex differences in over 50 cardio-metabolic traits in a panel of 100 diverse
inbred strains of mice. The results clearly showed that the effects of sex on both clinical …
inbred strains of mice. The results clearly showed that the effects of sex on both clinical …
Fgr kinase is required for proinflammatory macrophage activation during diet-induced obesity
…, R Martinez de Mena, KC Krishnan, C Jiménez… - Nature …, 2020 - nature.com
Proinflammatory macrophages are key in the development of obesity. In addition, reactive
oxygen species (ROS), which activate the Fgr tyrosine kinase, also contribute to obesity. Here …
oxygen species (ROS), which activate the Fgr tyrosine kinase, also contribute to obesity. Here …
[PDF][PDF] A strategy for discovery of endocrine interactions with application to whole-body metabolism
…, BW Parks, ED Kim, F Norheim, KC Krishnan… - Cell metabolism, 2018 - cell.com
Inter-tissue communication via secreted proteins has been established as a vital mechanism
for proper physiologic homeostasis. Here, we report a bioinformatics framework using a …
for proper physiologic homeostasis. Here, we report a bioinformatics framework using a …