User profiles for Katalin A Wilkinson
 | Katalin Andrea WilkinsonThe Francis Crick Institute Verified email at crick.ac.uk Cited by 15776 |
An interferon-inducible neutrophil-driven blood transcriptional signature in human tuberculosis
Tuberculosis (TB), caused by infection with Mycobacterium tuberculosis, is a major cause of
morbidity and mortality worldwide. Efforts to control it are hampered by difficulties with …
morbidity and mortality worldwide. Efforts to control it are hampered by difficulties with …
[HTML][HTML] Predictive value of interferon-γ release assays for incident active tuberculosis: a systematic review and meta-analysis
Background We aimed to assess whether interferon-γ release assays (IGRAs) can predict the
development of active tuberculosis and whether the predictive ability of these tests is better …
development of active tuberculosis and whether the predictive ability of these tests is better …
A single dose of vitamin D enhances immunity to mycobacteria
Rationale: Vitamin D was used to treat tuberculosis (TB) in the preantibiotic era. Prospective
studies to evaluate the effect of vitamin D supplementation on antimycobacterial immunity …
studies to evaluate the effect of vitamin D supplementation on antimycobacterial immunity …
IFN-γ-and TNF-independent vitamin D-inducible human suppression of mycobacteria: the role of cathelicidin LL-37
AR Martineau, KA Wilkinson, SM Newton… - The Journal of …, 2007 - journals.aai.org
Vitamin D deficiency is associated with susceptibility to tuberculosis, and its biologically
active metabolite, 1α, 25 dihydroxyvitamin D 3 (1α, 25 (OH) 2 D 3), has pleiotropic immune …
active metabolite, 1α, 25 dihydroxyvitamin D 3 (1α, 25 (OH) 2 D 3), has pleiotropic immune …
Enhanced contact tracing and spatial tracking of Mycobacterium tuberculosis infection by enumeration of antigen-specific T cells
A Lalvani, AA Pathan, H Durkan, KA Wilkinson… - The Lancet, 2001 - thelancet.com
Background Identification of individuals latently infected with Mycobacterium tuberculosis is
an important part of tuberculosis control. The current method, the tuberculin skin test (TST), …
an important part of tuberculosis control. The current method, the tuberculin skin test (TST), …
[HTML][HTML] Adaptive immunity and neutralizing antibodies against SARS-CoV-2 variants of concern following vaccination in patients with cancer: the CAPTURE study
Coronavirus disease 2019 (COVID-19) antiviral response in a pan-tumor immune monitoring
(CAPTURE) ( NCT03226886 ) is a prospective cohort study of COVID-19 immunity in …
(CAPTURE) ( NCT03226886 ) is a prospective cohort study of COVID-19 immunity in …
[HTML][HTML] Neutrophil-mediated innate immune resistance to mycobacteria
…, SM Newton, KA Wilkinson… - The Journal of …, 2007 - Am Soc Clin Investig
Neutrophils contain antimicrobial peptides with antituberculous activity, but their contribution
to immune resistance to tuberculosis (TB) infection has not been previously investigated to …
to immune resistance to tuberculosis (TB) infection has not been previously investigated to …
Direct ex vivo analysis of antigen-specific IFN-γ-secreting CD4 T cells in Mycobacterium tuberculosis-infected individuals: associations with clinical disease state and …
The wide spectrum of clinical outcomes following infection with Mycobacterium tuberculosis
is largely determined by the host immune response; therefore, we studied several clinically …
is largely determined by the host immune response; therefore, we studied several clinically …
Rapid detection of active and latent tuberculosis infection in HIV-positive individuals by enumeration of Mycobacterium tuberculosis-specific T cells
ALN Chapman, M Munkanta, KA Wilkinson, AA Pathan… - Aids, 2002 - journals.lww.com
Objectives: An accurate test for Mycobacterium tuberculosis infection is urgently needed. The
tuberculin skin test (TST) lacks sensitivity, particularly in HIV-infected individuals, and has …
tuberculin skin test (TST) lacks sensitivity, particularly in HIV-infected individuals, and has …
Enumeration of T Cells Specific for RD1-Encoded Antigens Suggests a High Prevalence of Latent Mycobacterium tuberculosis Infection in Healthy Urban Indians
…, Z Udwadia, AA Pathan, KA Wilkinson… - The Journal of …, 2001 - academic.oup.com
Abstract Knowledge of the prevalence of latent Mycobacterium tuberculosis infection is crucial
for effective tuberculosis control, but tuberculin skin test surveys have major limitations, …
for effective tuberculosis control, but tuberculin skin test surveys have major limitations, …