Regulation of the PI3K pathway through a p85α monomer–homodimer equilibrium

LWT Cheung, KW Walkiewicz, TMD Besong, H Guo… - Elife, 2015 - elifesciences.org
10.7554/eLife.06866.001 The canonical action of the p85α regulatory subunit of
phosphatidylinositol 3-kinase (PI3K) is to associate with the p110α catalytic subunit to allow stimuli-…

[PDF][PDF] Malondialdehyde (MDA)–product of lipid peroxidation as marker of homeostasis disorders and aging

…, KW Walkiewicz… - Annales Academiae …, 2016 - bibliotekanauki.pl
Malondialdehyde (MDA) found in the body comes from two sources: food consumed and lipid
peroxidation occurring in the tissues. The formation of MDA and the scale and rate of lipid …

[HTML][HTML] How to awaken your nanomachines: Site-specific activation of focal adhesion kinases through ligand interactions

KW Walkiewicz, JA Girault, ST Arold - Progress in biophysics and molecular …, 2015 - Elsevier
The focal adhesion kinase (FAK) and the related protein-tyrosine kinase 2-beta (Pyk2) are
highly versatile multidomain scaffolds central to cell adhesion, migration, and survival. Due to …

[HTML][HTML] Evaluation of malondialdehyde level, total oxidant/antioxidant status and oxidative stress index in colorectal cancer patients

K Janion, JK Strzelczyk, KW Walkiewicz, K Biernacki… - Metabolites, 2022 - mdpi.com
Oxidative stress may play an important role in colorectal cancer (CRC). The present study
included 94 adult patients with CRC (52 men and 42 women) and 26 hospitalized patients (12 …

[HTML][HTML] ADAM10 and ADAM17 as Biomarkers Linked to Inflammation, Metabolic Disorders and Colorectal Cancer

M Sikora-Skrabaka, KW Walkiewicz… - Current Issues in …, 2022 - mdpi.com
ADAM10 and ADAM17 have a role in inflammation and diseases associated with inflammation,
such as diabetes, cardiovascular diseases (CVD) or cancer, eg, colorectal cancer (CRC)…

Proteome-level assessment of origin, prevalence and function of leucine-aspartic acid (LD) motifs

…, AA Momin, V Astro, SB Hong, KW Walkiewicz… - …, 2020 - academic.oup.com
Motivation Leucine-aspartic acid (LD) motifs are short linear interaction motifs (SLiMs) that
link paxillin family proteins to factors controlling cell adhesion, motility and survival. The …

Proteome-level assessment of origin, prevalence and function of Leucine-Aspartic Acid (LD) motifs

…, R Naser, F Huser, AA Momin, KW Walkiewicz… - bioRxiv, 2018 - biorxiv.org
Short Linear Motifs (SLiMs) contribute to almost every cellular function by connecting
appropriate protein partners. Accurate prediction of SLiMs is difficult due to their shortness and …

Cognitive impairment in elderly patients considering concentration of hemoglobin and vitamin B12 – preliminary report

KW Walkiewicz, S Dzięgielewska-Gęsiak… - Family Medicine & …, 2015 - termedia.pl
Cel pracy. analiza korelacji między zaburzeniami poznawczymi, niedoborem witaminy B12
a anemią. Materiał i metody. Badanie przeprowadzono w grupie 48 chorych …

[PDF][PDF] Supplementary Material for: Proteome-level assessment of origin, prevalence and function of Leucine-Aspartic Acid (LD) motifs

…, R Naser, F Huser, AA Momin, KW Walkiewicz… - scienceopen.com
The following characterisation of all LDMF-identified proteins was obtained by combining
literature searches with four computational methods, namely PrePPI (a Bayesian framework …

[CITATION][C] tanviralambd/LD: Source code for LD motif detection

…, F Huser, AAI Momin, V Astro, S Hong, KW Walkiewicz… - 2019 - repository.kaust.edu.sa
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