[PDF][PDF] A taxonomy of transcriptomic cell types across the isocortex and hippocampal formation

…, SM Sunkin, M Tieu, A Torkelson, H Tung, K Ward… - Cell, 2021 - cell.com
The isocortex and hippocampal formation (HPF) in the mammalian brain play critical roles
in perception, cognition, emotion, and learning. We profiled ∼1.3 million cells covering the …

[HTML][HTML] Human neocortical expansion involves glutamatergic neuron diversification

…, J Trinh, H Tung, W Wakeman, F Waleboer, K Ward… - Nature, 2021 - nature.com
The neocortex is disproportionately expanded in human compared with mouse 1 , 2 , both
in its total volume relative to subcortical structures and in the proportion occupied by …

[PDF][PDF] Integrated morphoelectric and transcriptomic classification of cortical GABAergic cells

…, A Torkelson, J Trinh, H Tung, W Wakeman, K Ward… - Cell, 2020 - cell.com
Neurons are frequently classified into distinct types on the basis of structural, physiological,
or genetic attributes. To better constrain the definition of neuronal cell types, we …

[HTML][HTML] A high-resolution transcriptomic and spatial atlas of cell types in the whole mouse brain

…, N Valera Cuevas, S Vance, K Wadhwani, K Ward… - Nature, 2023 - nature.com
The mammalian brain consists of millions to billions of cells that are organized into many cell
types with specific spatial distribution patterns and structural and functional properties 1 , 2 …

Human cortical expansion involves diversification and specialization of supragranular intratelencephalic-projecting neurons

…, A Torkelson, J Trinh, H Tung, W Wakeman, K Ward… - BioRxiv, 2020 - biorxiv.org
The neocortex is disproportionately expanded in human compared to mouse, both in its total
volume relative to subcortical structures and in the proportion occupied by supragranular …

Toward an integrated classification of neuronal cell types: morphoelectric and transcriptomic characterization of individual GABAergic cortical neurons

…, A Torkelson, J Trinh, H Tung, W Wakeman, K Ward… - BioRxiv, 2020 - biorxiv.org
Neurons are frequently classified into distinct groups or cell types on the basis of structural,
physiological, or genetic attributes. To better constrain the definition of neuronal cell types, …

EEG biomarkers of target engagement, therapeutic effect, and disease process

…, MF McMullen, KR Ward… - Annals of the New …, 2015 - Wiley Online Library
Studies suggest that abnormalities in glutamate and GABA signaling contribute to deficits in
schizophrenia and related conditions and that these neurochemical abnormalities produce …

Racial differences in geographic access to medical care as measured by patient report and geographic information systems

…, N Mitra, A Radhakrishnan, CC Branas, KR Ward… - Medical care, 2017 - journals.lww.com
Background: Geographic access—the travel burden required to reach medical care—is an
important aspect of care. Studies, which typically rely on geographic information system (GIS) …

[HTML][HTML] Racial differences in prostate cancer treatment: the role of socioeconomic status

…, D Grande, A Radhakrishnan, N Mitra, KR Ward… - Ethnicity & …, 2017 - ncbi.nlm.nih.gov
Objective This study examines whether socioeconomic status (SES), measured at both the
individual and neighborhood levels, is associated with receipt of definitive treatment for …

A multidimensional view of racial differences in access to prostate cancer care

CE Pollack, KA Armstrong, N Mitra, X Chen, KR Ward… - Cancer, 2017 - Wiley Online Library
BACKGROUND Racial disparities in prostate cancer treatment and outcomes are widespread
and poorly understood. In the current study, the authors sought to determine whether …