User profiles for Katharine A. White

Katharine A. White

University of Notre Dame
Verified email at nd.edu
Cited by 1284

A fluorophore ligase for site-specific protein labeling inside living cells

C Uttamapinant, KA White, H Baruah… - Proceedings of the …, 2010 - National Acad Sciences
Biological microscopy would benefit from smaller alternatives to green fluorescent protein
for imaging specific proteins in living cells. Here we introduce PRIME (PRobe Incorporation …

Cancer cell behaviors mediated by dysregulated pH dynamics at a glance

KA White, BK Grillo-Hill, DL Barber - Journal of cell science, 2017 - journals.biologists.com
Dysregulated pH is a common characteristic of cancer cells, as they have an increased
intracellular pH (pH i ) and a decreased extracellular pH (pH e ) compared with normal cells. …

Yeast display evolution of a kinetically efficient 13-amino acid substrate for lipoic acid ligase

S Puthenveetil, DS Liu, KA White… - Journal of the …, 2009 - ACS Publications
Escherichia coli lipoic acid ligase (LplA) catalyzes ATP-dependent covalent ligation of lipoic
acid onto specific lysine side chains of three acceptor proteins involved in oxidative …

Site-specific protein labeling using PRIME and chelation-assisted click chemistry

…, MI Sanchez, DS Liu, JZ Yao, KA White… - Nature protocols, 2013 - nature.com
This protocol describes an efficient method to site-specifically label cell-surface or purified
proteins with chemical probes in two steps: probe incorporation mediated by enzymes (PRIME…

An exploration of perceived contraceptive coercion at the time of abortion

K Brandi, E Woodhams, KO White, PK Mehta - Contraception, 2018 - Elsevier
Objective To explore patient experiences of contraceptive coercion by healthcare providers
at time of abortion. Study Design We conducted a qualitative study of English-speaking …

Cancer-associated arginine-to-histidine mutations confer a gain in pH sensing to mutant proteins

KA White, DG Ruiz, ZA Szpiech, NB Strauli… - Science …, 2017 - science.org
The intracellular pH (pHi) of most cancers is constitutively higher than that of normal cells
and enhances proliferation and cell survival. We found that increased pHi enabled the …

Racism and the reproductive health experiences of US-born Black women

K Treder, KO White, E Woodhams… - Obstetrics & …, 2022 - journals.lww.com
OBJECTIVE: To explore Black women's lived experiences of racism and the associated effects
on reproductive health decisions and the reproductive health care experience. METHODS…

[HTML][HTML] Intracellular pH regulates cancer and stem cell behaviors: a protein dynamics perspective

Y Liu, KA White, DL Barber - Frontiers in Oncology, 2020 - frontiersin.org
The International Society of Cancer Metabolism (ISCaM) meeting on Cancer Metabolic
Rewiring, held in Braga Portugal in October 2019, provided an outstanding forum for …

An optogenetic tool to raise intracellular pH in single cells and drive localized membrane dynamics

CET Donahue, MD Siroky, KA White - Journal of the American …, 2021 - ACS Publications
Intracellular pH (pHi) dynamics are critical for regulating normal cell physiology. For example,
transient increases in pHi (7.2–7.6) regulate cell behaviors like cell polarization, actin …

[HTML][HTML] Obesity downregulates lipid metabolism genes in first trimester placenta

…, B Mathyk, T Kaneko-Tarui, D Roncari, KO White… - Scientific Reports, 2022 - nature.com
Placentas of obese women have low mitochondrial β-oxidation of fatty acids (FA) and
accumulate lipids in late pregnancy. This creates a lipotoxic environment, impairing placental …