The broad phylogenetic distribution and rapid phenotypic transitions of mammalian hibernators
imply that hibernation is accomplished by differential expression of common genes. …

Small-bodied hibernators partition the year between active homeothermy and hibernating
heterothermy accompanied by fasting. To define molecular events underlying hibernation that …

Hibernation in sciurid rodents is a dynamic phenotype timed by a circannual clock. When
housed in an animal facility, 13-lined ground squirrels exhibit variation in seasonal onset of …

10.7554/eLife.04517.001 During hibernation, animals cycle between torpor and arousal.
These cycles involve dramatic but poorly understood mechanisms of dynamic physiological …

The hibernator's heart functions continuously and avoids damage across the wide
temperature range of winter heterothermy. To define the molecular basis of this phenotype, we …

Hibernation is a physiological and behavioral phenotype that minimizes energy expenditure.
Hibernators cycle between profound depression and rapid hyperactivation of multiple …

During the hibernation season, 13-lined ground squirrels spend days to weeks in torpor with
body temperatures near freezing then spontaneously rewarm. The molecular drivers of the …

Background: We recently reported an association between Type 1 diabetes and the telomeric
major histocompatibility complex (MHC) single nucleotide polymorphism (SNP) rs1233478…

The daily rhythm of PERIOD (PER) protein expression is an integral component of the circadian
clock, which is found among a broad range of animal species including fruit flies, marine …

Hibernation is a highly dynamic phenotype whose timing, for many mammals, is controlled
by a circannual clock and accompanied by rhythms in body mass and food intake. When …