User profiles for Katherine A Pillman
Katherine A. PillmanHead of Gene Regulation Bioinformatics Group; Florey Fellow, Centre for Cancer Biology Verified email at unisa.edu.au Cited by 2780 |
[PDF][PDF] The RNA binding protein quaking regulates formation of circRNAs
Circular RNAs (circRNAs), formed by non-sequential back-splicing of pre-mRNA transcripts,
are a widespread form of non-coding RNA in animal cells. However, it is unclear whether …
are a widespread form of non-coding RNA in animal cells. However, it is unclear whether …
Genome‐wide identification of miR‐200 targets reveals a regulatory network controlling cell invasion
The micro RNA s of the miR‐200 family maintain the central characteristics of epithelia and
inhibit tumor cell motility and invasiveness. Using the Ago‐ HITS ‐ CLIP technology for …
inhibit tumor cell motility and invasiveness. Using the Ago‐ HITS ‐ CLIP technology for …
[HTML][HTML] Combinatorial targeting by microRNAs co-ordinates post-transcriptional control of EMT
MicroRNAs (miRNAs) are important post-transcriptional regulators of gene expression,
functioning in part by facilitating the degradation of target mRNAs. They have an established role …
functioning in part by facilitating the degradation of target mRNAs. They have an established role …
miR‐200/375 control epithelial plasticity‐associated alternative splicing by repressing the RNA‐binding protein Quaking
KA Pillman, CA Phillips, S Roslan, J Toubia… - The EMBO …, 2018 - embopress.org
Members of the miR‐200 family are critical gatekeepers of the epithelial state, restraining
expression of pro‐mesenchymal genes that drive epithelial–mesenchymal transition ( EMT ) …
expression of pro‐mesenchymal genes that drive epithelial–mesenchymal transition ( EMT ) …
Naturally existing isoforms of miR-222 have distinct functions
F Yu, KA Pillman, CT Neilsen, J Toubia… - Nucleic acids …, 2017 - academic.oup.com
Deep-sequencing reveals extensive variation in the sequence of endogenously expressed
microRNAs (termed ‘isomiRs’) in human cell lines and tissues, especially in relation to the 3…
microRNAs (termed ‘isomiRs’) in human cell lines and tissues, especially in relation to the 3…
[PDF][PDF] Post-transcriptional gene regulation by MicroRNA-194 promotes neuroendocrine transdifferentiation in prostate cancer
…, S Townley, AR Hanson, BK Dredge, KA Pillman… - Cell reports, 2021 - cell.com
Potent therapeutic inhibition of the androgen receptor (AR) in prostate adenocarcinoma can
lead to the emergence of neuroendocrine prostate cancer (NEPC), a phenomenon …
lead to the emergence of neuroendocrine prostate cancer (NEPC), a phenomenon …
[HTML][HTML] p53 represses the oncogenic Sno-MiR-28 derived from a SnoRNA
p53 is a master tumour repressor that participates in vast regulatory networks, including
feedback loops involving microRNAs (miRNAs) that regulate p53 and that themselves are direct …
feedback loops involving microRNAs (miRNAs) that regulate p53 and that themselves are direct …
Hv-CBF2A overexpression in barley accelerates COR gene transcript accumulation and acquisition of freezing tolerance during cold acclimation
Z Jeknić, KA Pillman, T Dhillon, JS Skinner… - Plant molecular …, 2014 - Springer
C-Repeat Binding Factors (CBFs) are DNA-binding transcriptional activators of gene
pathways imparting freezing tolerance. Poaceae contain three CBF subfamilies, two of which, …
pathways imparting freezing tolerance. Poaceae contain three CBF subfamilies, two of which, …
Assessing the gene regulatory properties of Argonaute-bound small RNAs of diverse genomic origin
DW Thomson, KA Pillman, ML Anderson… - Nucleic acids …, 2015 - academic.oup.com
High-throughput sequencing reveals an abundance of microRNA-sized fragments derived
from larger non-coding RNAs. Roles for these small RNAs in gene silencing are suggested by …
from larger non-coding RNAs. Roles for these small RNAs in gene silencing are suggested by …
miR-222 isoforms are differentially regulated by type-I interferon
Endogenous microRNAs (miRNAs) often exist as multiple isoforms (known as “isomiRs”)
with predominant variation around their 3′-end. Increasing evidence suggests that different …
with predominant variation around their 3′-end. Increasing evidence suggests that different …