User profiles for Katherine A Pillman

Katherine A. Pillman

Head of Gene Regulation Bioinformatics Group; Florey Fellow, Centre for Cancer Biology
Verified email at unisa.edu.au
Cited by 2780

[PDF][PDF] The RNA binding protein quaking regulates formation of circRNAs

SJ Conn, KA Pillman, J Toubia, VM Conn… - Cell, 2015 - cell.com
Circular RNAs (circRNAs), formed by non-sequential back-splicing of pre-mRNA transcripts,
are a widespread form of non-coding RNA in animal cells. However, it is unclear whether …

Genome‐wide identification of miR‐200 targets reveals a regulatory network controlling cell invasion

…, X Li, JA Wright, DM Lawrence, KA Pillman… - The EMBO …, 2014 - embopress.org
The micro RNA s of the miR‐200 family maintain the central characteristics of epithelia and
inhibit tumor cell motility and invasiveness. Using the Ago‐ HITS ‐ CLIP technology for …

[HTML][HTML] Combinatorial targeting by microRNAs co-ordinates post-transcriptional control of EMT

J Cursons, KA Pillman, KG Scheer, PA Gregory… - Cell systems, 2018 - cell.com
MicroRNAs (miRNAs) are important post-transcriptional regulators of gene expression,
functioning in part by facilitating the degradation of target mRNAs. They have an established role …

miR‐200/375 control epithelial plasticity‐associated alternative splicing by repressing the RNA‐binding protein Quaking

KA Pillman, CA Phillips, S Roslan, J Toubia… - The EMBO …, 2018 - embopress.org
Members of the miR‐200 family are critical gatekeepers of the epithelial state, restraining
expression of pro‐mesenchymal genes that drive epithelial–mesenchymal transition ( EMT ) …

Naturally existing isoforms of miR-222 have distinct functions

F Yu, KA Pillman, CT Neilsen, J Toubia… - Nucleic acids …, 2017 - academic.oup.com
Deep-sequencing reveals extensive variation in the sequence of endogenously expressed
microRNAs (termed ‘isomiRs’) in human cell lines and tissues, especially in relation to the 3…

[PDF][PDF] Post-transcriptional gene regulation by MicroRNA-194 promotes neuroendocrine transdifferentiation in prostate cancer

…, S Townley, AR Hanson, BK Dredge, KA Pillman… - Cell reports, 2021 - cell.com
Potent therapeutic inhibition of the androgen receptor (AR) in prostate adenocarcinoma can
lead to the emergence of neuroendocrine prostate cancer (NEPC), a phenomenon …

[HTML][HTML] p53 represses the oncogenic Sno-MiR-28 derived from a SnoRNA

F Yu, CP Bracken, KA Pillman, DM Lawrence… - PloS one, 2015 - journals.plos.org
p53 is a master tumour repressor that participates in vast regulatory networks, including
feedback loops involving microRNAs (miRNAs) that regulate p53 and that themselves are direct …

Hv-CBF2A overexpression in barley accelerates COR gene transcript accumulation and acquisition of freezing tolerance during cold acclimation

Z Jeknić, KA Pillman, T Dhillon, JS Skinner… - Plant molecular …, 2014 - Springer
C-Repeat Binding Factors (CBFs) are DNA-binding transcriptional activators of gene
pathways imparting freezing tolerance. Poaceae contain three CBF subfamilies, two of which, …

Assessing the gene regulatory properties of Argonaute-bound small RNAs of diverse genomic origin

DW Thomson, KA Pillman, ML Anderson… - Nucleic acids …, 2015 - academic.oup.com
High-throughput sequencing reveals an abundance of microRNA-sized fragments derived
from larger non-coding RNAs. Roles for these small RNAs in gene silencing are suggested by …

miR-222 isoforms are differentially regulated by type-I interferon

C Nejad, KA Pillman, KJ Siddle, G Pépin, ML Änkö… - Rna, 2018 - rnajournal.cshlp.org
Endogenous microRNAs (miRNAs) often exist as multiple isoforms (known as “isomiRs”)
with predominant variation around their 3′-end. Increasing evidence suggests that different …