We achieve simultaneous two-photon excitation of three chromophores with distinct absorption
spectra using synchronized pulses from a femtosecond laser and an optical parametric …

Understanding neural circuits requires deciphering interactions among myriad cell types
defined by spatial organization, connectivity, gene expression, and other properties. Resolving …

Large-scale microscopy approaches are transforming brain imaging, but currently lack
efficient multicolor contrast modalities. We introduce chromatic multiphoton serial (ChroMS) …

Diverse types of glutamatergic pyramidal neurons mediate the myriad processing streams
and output channels of the cerebral cortex 1 , 2 , yet all derive from neural progenitors of the …

We present a method to label and trace the lineage of multiple neural progenitors simultaneously
in vertebrate animals via multiaddressable genome-integrative color (MAGIC) markers. …

An essential step toward understanding brain function is to establish a structural framework
with cellular resolution on which multi-scale datasets spanning molecules, cells, circuits and …

Cell-type-specific expression of molecular tools and sensors is critical to construct circuit
diagrams and to investigate the activity and function of neurons within the nervous system. …

Oligodendrocyte precursor cells, which persist in the adult central nervous system, are the
main source of central nervous system remyelinating cells. In multiple sclerosis, some …

It is widely accepted that the angiotensin AT2-receptor (AT2R) has neuroprotective features.
In the present study we tested pharmacological AT2R-stimulation as a therapeutic approach …

The circuitry of the striatum is characterized by two organizational plans: the division into
striosome and matrix compartments, thought to mediate evaluation and action, and the direct …