User profiles for Katherine Woods

Katherine Woods

Malaghan Institute of Medical Research
Verified email at malaghan.org.nz
Cited by 2184

CMTM6 maintains the expression of PD-L1 and regulates anti-tumour immunity

…, CE Sparbier, YC Chan, JC Williamson, K Woods… - Nature, 2017 - nature.com
Cancer cells exploit the expression of the programmed death-1 (PD-1) ligand 1 (PD-L1) to
subvert T-cell-mediated immunosurveillance 1 , 2 . The success of therapies that disrupt PD-…

[HTML][HTML] Growth Hormone Insensitivity Associated with a STAT5b Mutation

EM Kofoed, V Hwa, B Little, KA Woods… - … England Journal of …, 2003 - Mass Medical Soc
This report documents that the syndrome of growth hormone insensitivity (severe short
stature, increased secretion of growth hormone, but low serum concentrations of insulin-like …

Butyrophilin 2A1 is essential for phosphoantigen reactivity by γδ T cells

…, S Ostrouska, TS Fulford, DN Johnson, K Woods… - Science, 2020 - science.org
INTRODUCTION T cells represent a key component of the immune system that can recognize
foreign molecules (antigens) via cognate cell surface receptors termed T cell receptors (…

[HTML][HTML] Intrauterine growth retardation and postnatal growth failure associated with deletion of the insulin-like growth factor I gene

KA Woods, C Camacho-Hübner… - … England Journal of …, 1996 - Mass Medical Soc
Insulin-like growth factor I (IGF-I) mediates the majority of the growth-promoting effects of
growth hormone (GH) after birth. In the prenatal period, GH does not appear to have a major …

[HTML][HTML] Coronavirus disease among persons with sickle cell disease, United States, March 20–May 21, 2020

…, F Yusuf, A Singh, B Taylor, K Woods… - Emerging Infectious …, 2020 - ncbi.nlm.nih.gov
Sickle cell disease (SCD) disproportionately affects Black or African American persons in the
United States and can cause multisystem organ damage and reduced lifespan. Among 178 …

MEK inhibition, alone or in combination with BRAF inhibition, affects multiple functions of isolated normal human lymphocytes and dendritic cells

…, AL Puaux, J Louahed, W Chen, K Woods… - Cancer immunology …, 2014 - AACR
Combination therapy with BRAF and MEK inhibition is currently in clinical development for
the treatment of BRAF-mutated malignant melanoma. BRAF inhibitors are associated with …

Heterozygous HESX1 mutations associated with isolated congenital pituitary hypoplasia and septo-optic dysplasia

…, F Cameron, J Hurst, K Woods… - Human molecular …, 2001 - academic.oup.com
We have previously shown that familial septo-optic dysplasia (SOD), a syndromic form of
congenital hypopituitarism involving optic nerve hypoplasia and agenesis of midline brain …

Comorbidities are risk factors for hospitalization and serious COVID-19 illness in children and adults with sickle cell disease

…, PM Simpson, A Singh, BW Taylor, KJ Woods… - Blood …, 2021 - ashpublications.org
Patients with sickle cell disease (SCD) are at high risk of developing serious infections,
therefore, understanding the impact that severe acute respiratory syndrome coronavirus 2 …

Cord blood leptin is associated with size at birth and predicts infancy weight gain in humans

…, ML Ahmed, A Sherriff, KA Woods… - The Journal of …, 1999 - academic.oup.com
Recent discoveries of human genetic leptin deficiency have demonstrated its importance in
regulating weight gain in early childhood. To investigate whether normal variation in leptin …

Isolation and characterization of NY-ESO-1–specific T cell receptors restricted on various MHC molecules

…, C Mathis, BH Moreno, K Woods… - Proceedings of the …, 2018 - National Acad Sciences
Tumor-specific T cell receptor (TCR) gene transfer enables specific and potent immune
targeting of tumor antigens. Due to the prevalence of the HLA-A2 MHC class I supertype in most …