User profiles for Kathleen L. Gould
Kathleen L. Gouldvanderbilt University Verified email at vanderbilt.edu Cited by 19568 |
Tyrosine phosphorylation of the fission yeast cdc2+ protein kinase regulates entry into mitosis
KL Gould, P Nurse - Nature, 1989 - nature.com
The cdc2 + protein kinase (pp34) is found to be phosphorylated on tyrosine as well as serine
and threonine residues in exponentially growing Schizosaccharomyces pombe. At mitosis, …
and threonine residues in exponentially growing Schizosaccharomyces pombe. At mitosis, …
Shotgun identification of protein modifications from protein complexes and lens tissue
…, JM Clark, JJ Tasto, KL Gould… - Proceedings of the …, 2002 - National Acad Sciences
Large-scale genomics has enabled proteomics by creating sequence infrastructures that can
be used with mass spectrometry data to identify proteins. Although protein sequences can …
be used with mass spectrometry data to identify proteins. Although protein sequences can …
Tyr527 Is Phosphorylated in pp60c-src: Implications for Regulation
The Rous sarcoma virus oncogene product, pp60 v-src , transforms cultured fibroblasts but
its corresponding proto-oncogene product, pp60 c-src , does not. Both proteins are known to …
its corresponding proto-oncogene product, pp60 c-src , does not. Both proteins are known to …
Phosphorylation at Thr167 is required for Schizosaccharomyces pombe p34cdc2 function.
Eukaryotic cell cycle progression requires the periodic activation and inactivation of a
protein‐serine/threonine kinase which in fission yeast is encoded by the cdc2+ gene. The activity …
protein‐serine/threonine kinase which in fission yeast is encoded by the cdc2+ gene. The activity …
The Arp2/3 complex: a multifunctional actin organizer
LM Machesky, KL Gould - Current opinion in cell biology, 1999 - Elsevier
The actin-related proteins (Arps) constitute a recently characterized family of proteins, many
of which function as members of multiprotein complexes. The discovery that two family …
of which function as members of multiprotein complexes. The discovery that two family …
Structural insights into the U-box, a domain associated with multi-ubiquitination
The structure of the U-box in the essential Saccharomyces cerevisiae pre-mRNA splicing
factor Prp19p has been determined by NMR. The conserved zinc-binding sites supporting the …
factor Prp19p has been determined by NMR. The conserved zinc-binding sites supporting the …
Role of polo kinase and Mid1p in determining the site of cell division in fission yeast
The fission yeast Schizosaccharomyces pombe divides symmetrically using a medial F-actin–
based contractile ring to produce equal-sized daughter cells. Mutants defective in two …
based contractile ring to produce equal-sized daughter cells. Mutants defective in two …
Substrate specificity of protein kinase C: use of synthetic peptides corresponding to physiological sites as probes for substrate recognition requirements
Although the Ca 2+ /phospholipid‐dependent protein kinase, protein kinase C, has a broad
substrate specificity in vitro, the enzyme appears considerably less promiscuous in vivo. To …
substrate specificity in vitro, the enzyme appears considerably less promiscuous in vivo. To …
Isolation and characterization of new fission yeast cytokinesis mutants
Schizosaccharomyces pombe is an excellent organism in which to study cytokinesis as it
divides by medial fission using an F-actin contractile ring. To enhance our understanding of the …
divides by medial fission using an F-actin contractile ring. To enhance our understanding of the …
Mapping and analysis of phosphorylation sites: a quick guide for cell biologists
A mechanistic understanding of signaling networks requires identification and analysis of
phosphorylation sites. Mass spectrometry offers a rapid and highly sensitive approach to …
phosphorylation sites. Mass spectrometry offers a rapid and highly sensitive approach to …