User profiles for Kathrin A. Otte

Kathrin A Otte

Professor for Population Genomics, University of Hamburg
Verified email at uni-hamburg.de
Cited by 788

[HTML][HTML] Genetic redundancy fuels polygenic adaptation in Drosophila

…, R Tobler, V Nolte, AM Jakšić, F Mallard, KA Otte… - PLoS …, 2019 - journals.plos.org
The genetic architecture of adaptive traits is of key importance to predict evolutionary
responses. Most adaptive traits are polygenic—ie, result from selection on a large number of …

[HTML][HTML] Progressive muscle proteome changes in a clinically relevant pig model of Duchenne muscular dystrophy

…, E Kemter, F Flenkenthaler, N Klymiuk, KA Otte… - Scientific reports, 2016 - nature.com
Duchenne muscular dystrophy (DMD) is caused by genetic deficiency of dystrophin and
characterized by massive structural and functional changes of skeletal muscle tissue, leading to …

Stage-specific proteome signatures in early bovine embryo development

DR Deutsch, T Fröhlich, KA Otte, A Beck… - Journal of proteome …, 2014 - ACS Publications
Development of early embryonic stages before activation of the embryonic genome
depends on sufficiently stored products of the maternal genome, adequate recruitment and …

[HTML][HTML] Proteomic analysis of Daphnia magna hints at molecular pathways involved in defensive plastic responses

KA Otte, T Fröhlich, GJ Arnold, C Laforsch - BMC genomics, 2014 - Springer
Background Phenotypic plasticity in defensive traits occurs in many species when facing
heterogeneous predator regimes. The waterflea Daphnia is well-known for showing a variety of …

Suitability of different mapping algorithms for genome-wide polymorphism scans with pool-seq data

…, AM Langmüller, P Nouhaud, KA Otte… - G3: Genes …, 2016 - academic.oup.com
The cost-effectiveness of sequencing pools of individuals (Pool-Seq) provides the basis for
the popularity and widespread use of this method for many research questions, ranging from …

[HTML][HTML] The genetic architecture of temperature adaptation is shaped by population ancestry and not by selection regime

KA Otte, V Nolte, F Mallard, C Schlötterer - Genome Biology, 2021 - Springer
Background Understanding the genetic architecture of temperature adaptation is key for
characterizing and predicting the effect of climate change on natural populations. One …

Neuronal Function and Dopamine Signaling Evolve at High Temperature in Drosophila

…, SK Hsu, N Barghi, F Mallard, KA Otte… - Molecular biology …, 2020 - academic.oup.com
Neuronal activity is temperature sensitive and affects behavioral traits important for
individual fitness, such as locomotion and courtship. Yet, we do not know enough about the …

Detecting selected haplotype blocks in evolve and resequence experiments

KA Otte, C Schlötterer - Molecular ecology resources, 2021 - Wiley Online Library
Shifting from the analysis of single nucleotide polymorphisms to the reconstruction of
selected haplotypes greatly facilitates the interpretation of evolve and resequence (E&R) …

Proteomic analysis of extracellular medium of cryopreserved carp (Cyprinus carpio L.) semen

MA Dietrich, GJ Arnold, T Fröhlich, KA Otte… - … and Physiology Part D …, 2015 - Elsevier
During freezing and thawing, spermatozoa are exposed to physical and chemical stressors
that result in adverse changes in sperm structures and physiological functions. The present …

Interclonal proteomic responses to predator exposure in Daphnia magna may depend on predator composition of habitats

KA Otte, I Schrank, T Fröhlich, GJ Arnold… - Molecular …, 2015 - Wiley Online Library
Phenotypic plasticity, the ability of one genotype to express different phenotypes in
response to changing environmental conditions, is one of the most common phenomena …