User profiles for Kathrin A. Otte
Kathrin A OtteProfessor for Population Genomics, University of Hamburg Verified email at uni-hamburg.de Cited by 788 |
[HTML][HTML] Genetic redundancy fuels polygenic adaptation in Drosophila
The genetic architecture of adaptive traits is of key importance to predict evolutionary
responses. Most adaptive traits are polygenic—ie, result from selection on a large number of …
responses. Most adaptive traits are polygenic—ie, result from selection on a large number of …
[HTML][HTML] Progressive muscle proteome changes in a clinically relevant pig model of Duchenne muscular dystrophy
Duchenne muscular dystrophy (DMD) is caused by genetic deficiency of dystrophin and
characterized by massive structural and functional changes of skeletal muscle tissue, leading to …
characterized by massive structural and functional changes of skeletal muscle tissue, leading to …
Stage-specific proteome signatures in early bovine embryo development
DR Deutsch, T Fröhlich, KA Otte, A Beck… - Journal of proteome …, 2014 - ACS Publications
Development of early embryonic stages before activation of the embryonic genome
depends on sufficiently stored products of the maternal genome, adequate recruitment and …
depends on sufficiently stored products of the maternal genome, adequate recruitment and …
[HTML][HTML] Proteomic analysis of Daphnia magna hints at molecular pathways involved in defensive plastic responses
Background Phenotypic plasticity in defensive traits occurs in many species when facing
heterogeneous predator regimes. The waterflea Daphnia is well-known for showing a variety of …
heterogeneous predator regimes. The waterflea Daphnia is well-known for showing a variety of …
Suitability of different mapping algorithms for genome-wide polymorphism scans with pool-seq data
The cost-effectiveness of sequencing pools of individuals (Pool-Seq) provides the basis for
the popularity and widespread use of this method for many research questions, ranging from …
the popularity and widespread use of this method for many research questions, ranging from …
[HTML][HTML] The genetic architecture of temperature adaptation is shaped by population ancestry and not by selection regime
Background Understanding the genetic architecture of temperature adaptation is key for
characterizing and predicting the effect of climate change on natural populations. One …
characterizing and predicting the effect of climate change on natural populations. One …
Neuronal Function and Dopamine Signaling Evolve at High Temperature in Drosophila
Neuronal activity is temperature sensitive and affects behavioral traits important for
individual fitness, such as locomotion and courtship. Yet, we do not know enough about the …
individual fitness, such as locomotion and courtship. Yet, we do not know enough about the …
Detecting selected haplotype blocks in evolve and resequence experiments
KA Otte, C Schlötterer - Molecular ecology resources, 2021 - Wiley Online Library
Shifting from the analysis of single nucleotide polymorphisms to the reconstruction of
selected haplotypes greatly facilitates the interpretation of evolve and resequence (E&R) …
selected haplotypes greatly facilitates the interpretation of evolve and resequence (E&R) …
Proteomic analysis of extracellular medium of cryopreserved carp (Cyprinus carpio L.) semen
MA Dietrich, GJ Arnold, T Fröhlich, KA Otte… - … and Physiology Part D …, 2015 - Elsevier
During freezing and thawing, spermatozoa are exposed to physical and chemical stressors
that result in adverse changes in sperm structures and physiological functions. The present …
that result in adverse changes in sperm structures and physiological functions. The present …
Interclonal proteomic responses to predator exposure in Daphnia magna may depend on predator composition of habitats
KA Otte, I Schrank, T Fröhlich, GJ Arnold… - Molecular …, 2015 - Wiley Online Library
Phenotypic plasticity, the ability of one genotype to express different phenotypes in
response to changing environmental conditions, is one of the most common phenomena …
response to changing environmental conditions, is one of the most common phenomena …