Pharmacological targeting of apelin impairs glioblastoma growth

E Harford-Wright, G Andre-Gregoire, KA Jacobs… - Brain, 2017 - academic.oup.com
Glioblastoma are highly aggressive brain tumours that are associated with an extremely
poor prognosis. Within these tumours exists a subpopulation of highly plastic self-renewing …

Pyridoxine deficiency in the human infant

…, LE HOLT JR, R CARRETERO, K Jacobs - The American Journal of …, 1953 - Elsevier
Pyridoxine deprivation in two human infants resulted in an arrest of weight gain and failure
of the ability to convert tryptophan to N 1 -methylnicotinamide in both. In one subject, it …

Role of WNT7B-induced noncanonical pathway in advanced prostate cancer

…, KF Decker, T Zhou, J Chen, Z Qi, K Jacobs… - Molecular Cancer …, 2013 - AACR
Advanced prostate cancer is characterized by incurable castration-resistant progression
and osteoblastic bone metastasis. While androgen deprivation therapy remains the primary …

From global change science to action with social sciences

…, T Fish, AE Grambsch, W Hohenstein, K Jacobs… - Nature Climate …, 2014 - nature.com
US efforts to integrate social and biophysical sciences to address the issue of global change
exist within a wider movement to understand global change as a societal challenge and to …

Paracaspase MALT1 regulates glioma cell survival by controlling endo‐lysosome homeostasis

KA Jacobs, G André‐Grégoire, C Maghe, A Thys… - The EMBO …, 2020 - embopress.org
Glioblastoma is one of the most lethal forms of adult cancer with a median survival of around
15 months. A potential treatment strategy involves targeting glioblastoma stem‐like cells ( …

[HTML][HTML] Lipid droplet degradation by autophagy connects mitochondria metabolism to Prox1-driven expression of lymphatic genes and lymphangiogenesis

…, M Borri, J Verhoeven, M Agrawal, K Jacobs… - Nature …, 2022 - nature.com
Autophagy has vasculoprotective roles, but whether and how it regulates lymphatic
endothelial cells (LEC) homeostasis and lymphangiogenesis is unknown. Here, we show that …

Gender issues in young adult literature

K Jacobs - 2004 - scholarworks.iupui.edu
Whether we are expanding our lives through knowledge or imagination, there is no doubt
that reading plays a crucial role in this process. Largely because of this, reading continues to …

[HTML][HTML] An autophagy program that promotes T cell egress from the lymph node controls responses to immune checkpoint blockade

D Houbaert, AP Nikolakopoulos, KA Jacobs, O Meçe… - Cell Reports, 2024 - cell.com
Lymphatic endothelial cells (LECs) of the lymph node (LN) parenchyma orchestrate leukocyte
trafficking and peripheral T cell dynamics. T cell responses to immunotherapy largely rely …

The Marriage Contract of the" Franklin's Tale:" The Remaking of Society

K Jacobs - The Chaucer Review, 1985 - JSTOR
When Dorigen and Arveragus promise each other marriage and much more, the Franklin has
scarcely finished thirty lines of his story. Critics (I among them) now habitually refer to their …

Studies on Rubella Immunization. 1. Demonstration of Rubella without Rash.

S Krugman, R Ward, KG Jacobs… - Journal of the American …, 1953 - cabdirect.org
Serum and nasopharyngeal washings from a patient suffering from rubella, taken 13 hours
after the appearance of the rash, were inoculated into children between the ages of 1 and 4 …