Whereas coding variants often have pleiotropic effects across multiple tissues, noncoding
variants are thought to mediate their phenotypic effects by specific tissue and temporal …

Genome-wide association studies (GWAS) have identified many disease-associated variants,
yet mechanisms underlying these associations remain unclear. To understand obesity-…

Diet is a key lifestyle component that influences metabolic health through several factors,
including total energy intake and macronutrient composition. While the impact of caloric intake …

Stress is a risk factor for many neuropsychiatric disorders, and the mesolimbic dopamine (DA)
pathway is a crucial node of vulnerability. Despite the high prevalence of stress-related …

The US Geological Survey (USGS) has compiled national shoreline data for more than 20
years to document coastal change and serve the needs of research, management, and the …

The research for this paper has been over forty years in the making as I first read the obituaries
of deceased Kentuckians in state and local newspapers beginning in 1972. A pattern …

Background To describe intensity‐modulated radiotherapy (IMRT) with Gamma Knife
Radiosurgery (GKRS) boost for locally advanced head and neck cancer (HNC) with disease near …

Obesity is a complex disease, with both environmental and genetic causes, and it confers a
significant global health burden while remaining difficult to treat and prevent. A better …

Introduction Immunotherapy and chemoimmunotherapy clinical trials for metastatic non–small-cell
lung cancer (mNSCLC) have generally excluded patients with poor performance …

In the USA, Black women participate in politics at much higher rates than expected, especially
given that the group ranks low on many of the traditional correlates of political participation…