Advanced age-related macular degeneration (AMD) is the leading cause of blindness in the
elderly, with limited therapeutic options. Here we report on a study of >12 million variants, …

Refractive error is the most common eye disorder worldwide and is a prominent cause of
blindness. Myopia affects over 30% of Western populations and up to 80% of Asians. The …

We report a genome-wide association study for open-angle glaucoma (OAG) blindness
using a discovery cohort of 590 individuals with severe visual field loss (cases) and 3,956 …

We conducted a genome-wide association study for primary open-angle glaucoma (POAG)
in 1,263 affected individuals (cases) and 34,877 controls from Iceland. We identified a …

Central corneal thickness (CCT) is associated with eye conditions including keratoconus and
glaucoma. We performed a meta-analysis on >20,000 individuals in European and Asian …

OBJECTIVE Diabetic retinopathy is a sight-threatening microvascular complication of diabetes
with a complex multifactorial pathogenesis. A systematic meta-analysis was undertaken …

Primary open-angle glaucoma (POAG) is a leading cause of blindness worldwide. To identify
new susceptibility loci, we performed meta-analysis on genome-wide association study (…

Most genetic susceptibility to cutaneous melanoma remains to be discovered. Meta-analysis
genome-wide association study (GWAS) of 36,760 cases of melanoma (67% newly …

Thirteen common susceptibility loci have been reproducibly associated with cutaneous
malignant melanoma (CMM). We report the results of an international 2-stage meta-analysis of …

Elevated intraocular pressure (IOP) is an important risk factor in developing glaucoma, and
variability in IOP might herald glaucomatous development or progression. We report the …