COVID survivors frequently experience lingering neurological symptoms that resemble
cancer-therapy-related cognitive impairment, a syndrome for which white matter microglial …

We collated data from 157 unpublished cases of pediatric high-grade glioma and diffuse
intrinsic pontine glioma and 20 publicly available datasets in an integrated analysis of >1,000 …

High-grade gliomas are lethal brain cancers whose progression is robustly regulated by
neuronal activity. Activity-regulated release of growth factors promotes glioma growth, but this …

Diffuse intrinsic pontine glioma (DIPG) is a fatal brain cancer that arises in the brainstem of
children, with no effective treatment and near 100% fatality. The failure of most therapies can …

Diffuse intrinsic pontine glioma (DIPG) is the most severe paediatric solid tumour, with no
significant therapeutic progress made in the past 50 years. Recent studies suggest that diffuse …

Diffuse intrinsic pontine gliomas (DIPGs) are highly infiltrative malignant glial neoplasms of
the ventral pons that, due to their location within the brain, are unsuitable for surgical …

Children and young adults with glioblastoma (GBM) have a median survival rate of only 12
to 15 months, and these GBMs are clinically and biologically distinct from histologically …

Diffuse intrinsic pontine glioma (DIPG) is a fatal pediatric cancer with limited therapeutic
options. The majority of cases of DIPG exhibit a mutation in histone-3 (H3K27M) that results in …

The tumour microenvironment plays an essential role in malignancy, and neurons have
emerged as a key component of the tumour microenvironment that promotes tumourigenesis …

Survivors of Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) infection
frequently experience lingering neurological symptoms, including impairment in attention, …