[HTML][HTML] Expanding the diversity of mycobacteriophages: insights into genome architecture and evolution

…, AR Schott, JB Segal, CD Shaffer, KE Sheldon… - PloS one, 2011 - journals.plos.org
Mycobacteriophages are viruses that infect mycobacterial hosts such as Mycobacterium
smegmatis and Mycobacterium tuberculosis. All mycobacteriophages characterized to date are …

[PDF][PDF] A requirement for the Saccharomyces cerevisiae Paf1 complex in snoRNA 3′ end formation

KE Sheldon, DM Mauger, KM Arndt - Molecular cell, 2005 - cell.com
RNA synthesis and processing are coordinated by proteins that associate with RNA polymerase
II (pol II) during transcription elongation. The yeast Paf1 complex interacts with RNA pol …

Shaping the murine macrophage phenotype: IL-4 and cyclic AMP synergistically activate the arginase I promoter

KE Sheldon, H Shandilya, D Kepka-Lenhart… - The Journal of …, 2013 - journals.aai.org
Arginase I is a marker of murine M2 macrophages and is highly expressed in many
inflammatory diseases. The basis for high arginase I expression in macrophages in vivo is …

Paenibacillus infection with frequent viral coinfection contributes to postinfectious hydrocephalus in Ugandan infants

…, J Onen, MR Peterson, F Roy, K Sheldon… - Science translational …, 2020 - science.org
Postinfectious hydrocephalus (PIH), which often follows neonatal sepsis, is the most common
cause of pediatric hydrocephalus worldwide, yet the microbial pathogens underlying this …

Mutational profile of endometrial hyperplasia and risk of progression to endometrioid adenocarcinoma

…, JM Newell, L Budurlean, KR Houser, K Sheldon… - Cancer, 2020 - Wiley Online Library
Background Endometrial hyperplasia is a precursor to endometrioid adenocarcinoma (EMC),
the most common uterine cancer. The likelihood of progression to carcinoma may be …

Identification of a rare LAMB4 variant associated with familial diverticulitis through exome sequencing

JL Coble, KE Sheldon, F Yue… - Human molecular …, 2017 - academic.oup.com
Diverticulitis is a chronic disease of the colon in which diverticuli, or outpouching through the
colonic wall, become inflamed. Although recent observations suggest that genetic factors …

Neonatal Paenibacilliosis: Paenibacillus Infection as a Novel Cause of Sepsis in Term Neonates With High Risk of Sequelae in Uganda

…, P Olupot-Olupot, J Onen, K Sheldon… - Clinical Infectious …, 2023 - academic.oup.com
Background Paenibacillus thiaminolyticus may be an underdiagnosed cause of neonatal
sepsis. Methods We prospectively enrolled a cohort of 800 full-term neonates presenting with a …

Clonal evolution in paired endometrial intraepithelial neoplasia/atypical hyperplasia and endometrioid adenocarcinoma

M Russo, J Broach, K Sheldon, KR Houser, DJ Liu… - Human pathology, 2017 - Elsevier
Endometrial intraepithelial neoplasia (EIN) and atypical endometrial hyperplasia (AH) are
histomorphologically defined precursors to endometrioid adenocarcinoma, which are unified …

[HTML][HTML] Vaginal microbiome topic modeling of laboring Ugandan women with and without fever

…, C Hehnly, L Zhang, K Moran, K Sheldon… - npj Biofilms and …, 2021 - nature.com
The composition of the maternal vaginal microbiome influences the duration of pregnancy,
onset of labor, and even neonatal outcomes. Maternal microbiome research in sub-Saharan …