PharmGKB summary: methotrexate pathway

…, S Marsh, HL McLeod, K Giacomini… - Pharmacogenetics …, 2011 - journals.lww.com
Methotrexate is a folate analog that is used in the treatment of cancers (eg acute lymphoblastic
leukemia, non-Hodgkin lymphoma, osteosarcoma, and colon cancer) and autoimmune …

Phase I Study of Vorinostat as a Radiation Sensitizer with 131I-Metaiodobenzylguanidine (131I-MIBG) for Patients with Relapsed or Refractory Neuroblastoma

…, X Yang, E Geier, E Chen, K Giacomini… - Clinical Cancer …, 2015 - AACR
Purpose: 131 I-metaiodobenzylguanidine (MIBG) is a radiopharmaceutical with activity in
neuroblastoma. Vorinostat is a histone deacetylase inhibitor that has radiosensitizing …

Vesicular monoamine transporter protein expression correlates with clinical features, tumor biology, and MIBG avidity in neuroblastoma: a report from the Children's …

…, E Nekritz, WC Gustafson, L Lin, K Giacomini… - European journal of …, 2016 - Springer
Purpose Vesicular monoamine transporters 1 and 2 (VMAT1 and VMAT2) are thought to
mediate MIBG uptake in adult neuroendocrine tumors. In neuroblastoma, the norepinephrine …

Pharm. D. pathways to biomedical research: the National Institutes of Health special conference on pharmacy research

…, P Taylor, J Cohen, K Giacomini - … : The Journal of …, 2008 - Wiley Online Library
To address the shortage of research‐trained pharmaceutical scientists (or doctor of pharmacy
[Pharm.D.] scientists), a 2‐day pharmacy research conference titled “Pharm.D. Pathways …

The effects of personal pharmacogenetic testing on the effects of pharmacy student perceptions of knowledge and attitudes towards precision medicine

…, T Desai, BJ Guglielmo, K Giacomini… - INNOVATIONS in …, 2017 - pubs.lib.umn.edu
Objective: To evaluate if pharmacy students’ participation in personal pharmacogenetic (Pgx)
testing enhances their knowledge and attitude towards precision medicine (PM). Methods: …

Response to Comment on Dawed et al. Genome-Wide Meta-analysis Identifies Genetic Variants Associated With Glycemic Response to Sulfonylureas. Diabetes Care …

…, Ivan Tkac, Jose Florez, Kathy Giacomini… - Diabetes …, 2022 - Am Diabetes Assoc
We appreciate the opportunity to respond to the letter by Wang et al.(1) regarding our article
in a recent issue of Diabetes Care (2). In responding to the authors’ critique, we should first …

The Resource Allocation Program at the University of California, San Francisco: Getting More from Intramural Funding Bucks.

E Volpe, G Kiser, R Henry, K Giacomini… - Journal of Research …, 2014 - ERIC
Intramural funding programs within both large and small research institutions are an essential
mechanism to foster collaborative, novel, or preliminary research activity, and to further …

Personal pharmacogenetic testing enhances pharmacy student knowledge and attitude towards precision medicine

…, M Li, S Guo, T Desai, BJ Guglielmo, K Giacomini… - bioRxiv, 2016 - biorxiv.org
Objective To evaluate if pharmacy students’ participation in personal pharmacogenetic (Pgx)
testing enhances their knowledge and attitude towards precision medicine (PM). Methods …

[PDF][PDF] 1Department of Bioengineering and Therapeutic Sciences, and 2California Institute for Quantitative Biosciences, and 3Department of Pharmaceutical Chemistry …

A Schlessinger, N Khuri, K Giacomini… - To my husband Sami …, 2014 - escholarship.org
Solute Carrier (SLC) transporters are membrane proteins that transport solutes, such as ions,
metabolites, peptides, and drugs, across biological membranes, using diverse energy …

Vesicular monoamine transporter protein expression in neuroblastoma: A report from the Children's Oncology Group.

…, GE Kim, E Nekritz, C Gustafson, L Lin, K Giacomini… - 2015 - ascopubs.org
10043 Background: Vesicular monoamine transporters 1 and 2 (VMAT1 and VMAT2) are
thought to mediate MIBG uptake in adult neuroendocrine tumors. VMAT expression has not …