Cardiac injury and dysfunction occur in COVID-19 patients and increase the risk of mortality.
Causes are ill defined but could be through direct cardiac infection and/or inflammation-…

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) primarily infects the
respiratory tract, but pulmonary and cardiac complications occur in severe coronavirus disease …

Muscle contraction is driven by the molecular machinery of the sarcomere. As phosphorylation
is a critical regulator of muscle function, the identification of regulatory kinases is …

Recent studies in non-human model systems have shown therapeutic potential of
nucleoside-modified messenger RNA (modRNA) treatments for lysosomal storage diseases. Here, …

Background Anthracyclines are a mainstay of chemotherapy. However, a relatively frequent
adverse outcome of anthracycline treatment is cardiomyopathy. Multiple genetic studies …

SARS-CoV-2 primarily infects the respiratory tract, but pulmonary and cardiac complications
occur in severe COVID-19. To elucidate molecular mechanisms in the lung and heart, we …

SARS-CoV2 infection leads to cardiac injury and dysfunction in 20-30% of hospitalized patients
1 and higher rates of mortality in patients with pre-existing cardiovascular disease 2 , 3 . …

Cardiac injury and dysfunction occur in COVID-19 patients and increase the risk of mortality.
Causes are ill defined, but could be direct cardiac infection and/or ‘cytokine-storm’induced …

SARS-CoV-2 primarily infects the respiratory tract, but pulmonary and cardiac complications
occur in severe COVID-19. To elucidate molecular mechanisms in the lung and heart, we …

… Richard Mills; Sean Humphrey; Patrick RJ Fortuna; Gregory Quaife-Ryan; Mary Lor; Rajeev
Ruraraju; Daniel Rawle; Thuy Le; Wei Zhao; Leo Lee; Charley Mackenzie-Kludas; Neda …