Conjunctive input processing drives feature selectivity in hippocampal CA1 neurons
Feature-selective firing allows networks to produce representations of the external and
internal environments. Despite its importance, the mechanisms generating neuronal feature …
internal environments. Despite its importance, the mechanisms generating neuronal feature …
Behavioral time scale synaptic plasticity underlies CA1 place fields
Learning is primarily mediated by activity-dependent modifications of synaptic strength within
neuronal circuits. We discovered that place fields in hippocampal area CA1 are produced …
neuronal circuits. We discovered that place fields in hippocampal area CA1 are produced …
Inhibitory suppression of heterogeneously tuned excitation enhances spatial coding in CA1 place cells
Place cells in the CA1 region of the hippocampus express location-specific firing despite
receiving a steady barrage of heterogeneously tuned excitatory inputs that should compromise …
receiving a steady barrage of heterogeneously tuned excitatory inputs that should compromise …
[PDF][PDF] Axonal filtering allows reliable output during dendritic plateau-driven complex spiking in CA1 neurons
PF Apostolides, AD Milstein, C Grienberger, KC Bittner… - Neuron, 2016 - cell.com
In CA1 pyramidal neurons, correlated inputs trigger dendritic plateau potentials that drive
neuronal plasticity and firing rate modulation. Given the strong electrotonic coupling between …
neuronal plasticity and firing rate modulation. Given the strong electrotonic coupling between …
Bidirectional synaptic plasticity rapidly modifies hippocampal representations
Learning requires neural adaptations thought to be mediated by activity-dependent synaptic
plasticity. A relatively non-standard form of synaptic plasticity driven by dendritic calcium …
plasticity. A relatively non-standard form of synaptic plasticity driven by dendritic calcium …
[HTML][HTML] " Hyperglutamatergic cortico-striato-thalamo-cortical circuit" breaker drugs alleviate tics in a transgenic circuit model of Tourette׳ s syndrome
EJ Nordstrom, KC Bittner, MJ McGrath, CR Parks III… - Brain research, 2015 - Elsevier
The brain circuits underlying tics in Tourette׳s syndrome (TS) are unknown but thought to
involve cortico/amygdalo-striato-thalamo-cortical (CSTC) loop hyperactivity. We previously …
involve cortico/amygdalo-striato-thalamo-cortical (CSTC) loop hyperactivity. We previously …
[HTML][HTML] Ion channel gradients in the apical tuft region of CA1 pyramidal neurons
KC Bittner, BK Andrasfalvy, JC Magee - 2012 - journals.plos.org
Dendritic ion channels play a critical role in shaping synaptic input and are fundamentally
important for synaptic integration and plasticity. In the hippocampal region CA1, somato-…
important for synaptic integration and plasticity. In the hippocampal region CA1, somato-…
Mild traumatic brain injury induced by primary blast overpressure produces dynamic regional changes in [18F] FDG uptake
Abstract Changes in 18 F-fluorodeoxyglucose ([ 18 F]FDG) measured by positron emission
tomography (PET) can be used for the noninvasive detection of metabolic dysfunction …
tomography (PET) can be used for the noninvasive detection of metabolic dysfunction …
Discordance between documented criteria and documented diagnosis of traumatic brain injury in the emergency department
MR Cota, AD Moses, NR Jikaria, KC Bittner… - Journal of …, 2019 - liebertpub.com
Accurate diagnosis of traumatic brain injury (TBI) is critical to ensure that patients receive
appropriate follow-up care, avoid risk of subsequent injury, and are aware of possible long-…
appropriate follow-up care, avoid risk of subsequent injury, and are aware of possible long-…
[PDF][PDF] Current perspectives on the use of fetal fibronectin testing in preterm labor diagnosis and management
MS Ruma, KC Bittner, CB Soh - Am. J. Manag. Care, 2017 - researchgate.net
CURRENT PERSPECTIVES ON THE USE OF fFN TESTING overstated. This paper examines
several clinical guidelines, algorithms, and additional evidence from published studies …
several clinical guidelines, algorithms, and additional evidence from published studies …