User profiles for Katie N. Kang

Katie N. Kang

UT Southwestern Medical Center
Verified email at UTSouthwestern.edu
Cited by 140

Colistin heteroresistance in Enterobacter cloacae is regulated by PhoPQ‐dependent 4‐amino‐4‐deoxy‐l‐arabinose addition to lipid A

KN Kang, DR Klein, MI Kazi, F Guérin… - Molecular …, 2019 - Wiley Online Library
The Enterobacter cloacae complex (ECC) consists of closely related bacteria commonly
associated with the human microbiota. ECC are increasingly isolated from healthcare‐…

Peptidoglycan recycling promotes outer membrane integrity and carbapenem tolerance in Acinetobacter baumannii

N Islam, MI Kazi, KN Kang, J Biboy, J Gray, F Ahmed… - Mbio, 2022 - Am Soc Microbiol
β-Lactam antibiotics exploit the essentiality of the bacterial cell envelope by perturbing the
peptidoglycan layer, typically resulting in rapid lysis and death. Many Gram-negative bacteria …

Septal Class A Penicillin-Binding Protein Activity and ld-Transpeptidases Mediate Selection of Colistin-Resistant Lipooligosaccharide-Deficient Acinetobacter …

KN Kang, MI Kazi, J Biboy, J Gray, H Bovermann… - MBio, 2021 - Am Soc Microbiol
Despite dogma suggesting that lipopolysaccharide/lipooligosaccharide (LOS) was essential
for viability of Gram-negative bacteria, several Acinetobacter baumannii clinical isolates …

Discovery and characterization of New Delhi metallo-β-lactamase-1 inhibitor peptides that potentiate meropenem-dependent killing of carbapenemase-producing …

…, VC Obuekwe, M Sapkota, KN Kang… - Journal of …, 2020 - academic.oup.com
Objectives Metallo-β-lactamases (MBLs) are an emerging class of antimicrobial resistance
enzymes that degrade β-lactam antibiotics, including last-resort carbapenems. Infections …

PBP1A directly interacts with the divisome complex to promote septal peptidoglycan synthesis in Acinetobacter baumannii

KN Kang, JM Boll - Journal of Bacteriology, 2022 - Am Soc Microbiol
The class A penicillin-binding proteins (aPBPs), PBP1A and PBP1B, are major peptidoglycan
synthases that synthesize more than half of the peptidoglycan per generation in …

Peptidoglycan recycling contributes to outer membrane integrity and carbapenem tolerance in Acinetobacter baumannii

N Islam, MI Kazi, KN Kang, J Biboy, J Gray, F Ahmed… - bioRxiv, 2021 - biorxiv.org
The Gram-negative cell envelope is an essential structure that not only protects the cell against
lysis from the internal turgor, but also forms a barrier to limit entry of antibiotics. Some of …

Colistin heteroresistance in Enterobacter cloacae is mediated by PmrAB-independent 4-amino-4-deoxy-L-arabinose addition to lipid A

KN Kang, DR Klein, MI Kazi, F Guérin, V Cattoir… - bioRxiv, 2019 - biorxiv.org
The Enterobacter cloacae complex (ECC) consists of closely-related, but genetically distinct
bacteria commonly associated with the human microbiota. ECC have been increasingly …

Mechanistic insights into Gram-negative envelope remodeling for protection against severe outer membrane defects

KN Kang - 2022 - search.proquest.com
Gram-negative bacteria account for the majority of antibiotic resistant infections. Regulated
modifications within the cell envelope can promote resistance to clinically important antibiotics…

[HTML][HTML] α-Synuclein in blood exosomes immunoprecipitated using neuronal and oligodendroglial markers distinguishes Parkinson's disease from multiple system …

…, CH Adler, SL Perlman, WW Poon, UJ Kang… - Acta …, 2021 - Springer
The diagnosis of Parkinson’s disease (PD) and atypical parkinsonian syndromes is difficult
due to the lack of reliable, easily accessible biomarkers. Multiple system atrophy (MSA) is a …

[CITATION][C] Outer membrane integrity and peptidoglycan recycling promote carbapenem tolerance in Acinetobacter baumannii

N Islam, MI Kazi, KN Kang, J Biboy, J Gray, F Ahmed… - mBio, 2022 - eprints.ncl.ac.uk
b-Lactam antibiotics exploit the essentiality of the bacterial cell envelope by perturbing the
peptidoglycan layer, typically resulting in rapid lysis and death. Many Gram-negative bacteria …