Mouse and nonhuman primate models now serve as useful platforms to study Zika virus (ZIKV)
pathogenesis, candidate therapies, and vaccines, but they rely on needle inoculation of …

Developing biological interventions to control human immunodeficiency virus (HIV) replication
in the absence of antiretroviral therapy (ART) could contribute to the development of a …

Defining the complex dynamics of Zika virus (ZIKV) infection in pregnancy and during
transmission between vertebrate hosts and mosquito vectors is critical for a thorough …

Background: Alzheimer’s disease (AD) is the most common aging-associated neurodegenerative
disease; nevertheless, the etiology and progression of the disease is still incompletely …

Multistep synthesis is a key capstone experience in organic laboratory instruction. Here, a
four-step synthesis of avobenzone, an active component in sunscreens, has been developed …

For more than three decades it has been recognized that small amounts of vector saliva can
significantly alter the infectivity of vector-borne pathogens and subsequent in vivo dynamics. …

Age-related disease may be mediated by low levels of chronic inflammation (“inflammaging”).
Recent work suggests that gut microbes can contribute to inflammation via degradation of …

Background Dietary patterns appear to impact cognitive trajectories in aging, and gut
microbiota have been implicated in Alzheimer’s disease (AD) pathogenesis, potentially as …

Background Gut microbial composition is associated with Alzheimer’s disease (AD) pathology,
and recent findings (Heston et al, medRxiv 2022) have identified an increase in intestinal …

Background Using gnotobiotic models, our research group has demonstrated that specific
changes in the gut microbiome modulate serum and brain b‐hydroxybutyrate (BHB) levels. …