We performed exome sequencing to detect somatic mutations in protein-coding regions in
seven melanoma cell lines and donor-matched germline cells. All melanoma samples had …

Purpose: To investigate the mechanism(s) of resistance to the RAF-inhibitor vemurafenib,
we conducted a comprehensive analysis of the genetic alterations occurring in metastatic …

To delineate the role of the melanocyte lineage‐specific protein Melan‐A/MART‐1 in
melanogenic functions, a set of biochemical and microscopical studies was performed. …

The secreted growth factor Activin-A of the transforming growth factor β family and its receptors
can promote or inhibit several cancer hallmarks including tumor cell proliferation and …

The production of pigment by melanocytic cells of the skin involves a series of enzymatic
reactions that take place in specialized organelles called melanosomes. Melan-A/MART-1 is a …

The peptide derived from the melanoma-associated protein Melan-A (Melan-A 26–35 /HLA-A2)
is an attractive candidate for tumor immunotherapy but little is known about the …

Over the past few decades, Fourier transform infrared (FTIR) spectroscopy coupled to microscopy
has been recognized as an emerging and potentially powerful tool in cancer research …

… Montandon for help with cell culture experiments; Katja Muehlethaler for producing melanoma
cell lines; and Rébecca Panes for help with the preparation of the NanoString experiment. …

… We are very grateful to Katja Muehlethaler (Ludwig Institute for Cancer Research, Lausanne);
Alexandra Potts (UNIL Protein Analysis Facility) and Marianne Wicht, Nathalie Besuchet-…

Immunotherapy is being proposed to treat patients with hepatocellular carcinoma (HCC).
However, more detailed knowledge on tumor Ag expression and specific immune cells is …