[HTML][HTML] Transcriptomics-driven metabolic pathway analysis reveals similar alterations in lipid metabolism in mouse MASH model and human
…, P Kumar, P Seubnooch, K Freiburghaus… - Communications …, 2024 - nature.com
Background Metabolic dysfunction-associated steatotic liver disease (MASLD) is a
prevalent chronic liver disease worldwide, and can rapidly progress to metabolic dysfunction-…
prevalent chronic liver disease worldwide, and can rapidly progress to metabolic dysfunction-…
[HTML][HTML] Serum metabolites as biomarkers in systemic sclerosis-associated interstitial lung disease
C Meier, K Freiburghaus, C Bovet, J Schniering… - Scientific reports, 2020 - nature.com
Systemic sclerosis (SSc) is a severe multi-organ disease with interstitial lung disease (ILD)
being the major cause of death. While targeted therapies are emerging, biomarkers for sub-…
being the major cause of death. While targeted therapies are emerging, biomarkers for sub-…
Specific GAG ratios in the diagnosis of mucopolysaccharidoses
…, L Arackal, H Zhang, S Kurth, K Freiburghaus… - JIMD …, 2024 - Wiley Online Library
Mucopolysaccharidoses (MPS) screening is tedious and still performed by analysis of total
glycosaminoglycans (GAG) using 1,9‐dimethylmethylene blue (DMB) photometric assay, …
glycosaminoglycans (GAG) using 1,9‐dimethylmethylene blue (DMB) photometric assay, …
Metabolomics by UHPLC–MS: Benefits provided by complementary use of Q-TOF and QQQ for pathway profiling
K Freiburghaus, CR Largiadèr, C Stettler, GM Fiedler… - Metabolomics, 2019 - Springer
Introduction Non-targeted metabolic profiling using high-resolution mass spectrometry (HRMS)
is a standard approach for pathway identification despite technical limitations. Objectives …
is a standard approach for pathway identification despite technical limitations. Objectives …
Effects of Freezing and Thawing Procedures on Selected Clinical Chemistry Parameters in Plasma
K Freiburghaus, AB Leichtle, CT Nakas… - Biopreservation and …, 2020 - liebertpub.com
Introduction: Measurements from frozen sample collections are important key indicators in
clinical studies. It is a prime concern of biobanks and laboratories to minimize preanalytical …
clinical studies. It is a prime concern of biobanks and laboratories to minimize preanalytical …
Compartmentalization of intestinal bacteria by hepatic ILC3s prevents infections after surgery
…, C Mooser, S Daniel, LA Salm, K Freiburghaus… - bioRxiv, 2019 - biorxiv.org
Infections after surgical interventions are assumed to be caused by contamination. We show
by analyzing multicentric data of 6561 patients that surgical infections as well as sepsis had …
by analyzing multicentric data of 6561 patients that surgical infections as well as sepsis had …
Sat0334 pericardial involvement in systemic sclerosis
PM Álvarez, C De la Puente Bujidos - 2020 - ard.bmj.com
Background: Systemic sclerosis (SSc) is an autoimmune rheumatic disease characterized
by visceral and skin fibrosis, vascular dysfunction, and immune dysregulation. Regarding …
by visceral and skin fibrosis, vascular dysfunction, and immune dysregulation. Regarding …
Long-term protection after stopping venom immunotherapy: results of re-stings in 200 patients
E Lerch, UR Müller - Journal of allergy and clinical immunology, 1998 - Elsevier
Background: Venom immunotherapy (VIT) protects most patients allergic to Hymenoptera
stings while booster injections are continued. Few data on long-term protection after …
stings while booster injections are continued. Few data on long-term protection after …
Evaluation of IgG RAST® FEIA for the Assay of Venom–Specific IgG Antibodies during Venom Immunotherapy
P Meier, U Müller - International archives of allergy and immunology, 1998 - karger.com
Background: Successful venom immunotherapy (VIT) in Hymenoptera allergy is usually
associated with a strong increase in venom–specific serum IgG antibodies (sIgG). Methods: We …
associated with a strong increase in venom–specific serum IgG antibodies (sIgG). Methods: We …
[HTML][HTML] Outcome after discontinuing long-term benzimidazole treatment in 11 patients with non-resectable alveolar echinococcosis with negative FDG-PET/CT and …
RW Ammann, KDM Stumpe, F Grimm… - PLoS neglected …, 2015 - journals.plos.org
Background/Aims Benzimidazoles are efficacious for treating non-resectable alveolar
echinococcosis (AE), but their long-term parasitocidal (curative) effect is disputed. In this study, we …
echinococcosis (AE), but their long-term parasitocidal (curative) effect is disputed. In this study, we …