[HTML][HTML] TET1-mediated DNA hydroxymethylation regulates adult remyelination in mice
…, D Marechal, D Huang, KLH Marshall-Phelps… - Nature …, 2021 - nature.com
The mechanisms regulating myelin repair in the adult central nervous system (CNS) are
unclear. Here, we identify DNA hydroxymethylation, catalyzed by the Ten-Eleven-Translocation (…
unclear. Here, we identify DNA hydroxymethylation, catalyzed by the Ten-Eleven-Translocation (…
An automated high-resolution in vivo screen in zebrafish to identify chemical regulators of myelination
JJ Early, KLH Marshall-Phelps, JM Williamson, M Swire… - elife, 2018 - elifesciences.org
10.7554/eLife.35136.001 Myelinating oligodendrocytes are essential for central nervous
system (CNS) formation and function. Their disruption is implicated in numerous …
system (CNS) formation and function. Their disruption is implicated in numerous …
[HTML][HTML] Neuronal activity disrupts myelinated axon integrity in the absence of NKCC1b
KLH Marshall-Phelps, L Kegel, M Baraban… - Journal of Cell …, 2020 - rupress.org
Through a genetic screen in zebrafish, we identified a mutant with disruption to myelin in both
the CNS and PNS caused by a mutation in a previously uncharacterized gene, slc12a2b, …
the CNS and PNS caused by a mutation in a previously uncharacterized gene, slc12a2b, …
[HTML][HTML] Cerebellar molecular layer interneurons are dispensable for cued and contextual fear conditioning
KLH Marshall-Phelps, G Riedel, P Wulff… - Scientific reports, 2020 - nature.com
Purkinje cells are the only output cell of the cerebellar cortex. Their spatiotemporal activity is
controlled by molecular layer interneurons (MLIs) through GABA A receptor-mediated …
controlled by molecular layer interneurons (MLIs) through GABA A receptor-mediated …
TET1-mediated DNA hydroxy-methylation regulates adult remyelination
S Moyon, R Frawley, KLH Marshall-Phelps, L Kegel… - BioRxiv, 2019 - biorxiv.org
Adult myelination is essential for brain function and response to injury, but the molecular
mechanisms remain elusive. Here we identify DNA hydroxy-methylation, an epigenetic mark …
mechanisms remain elusive. Here we identify DNA hydroxy-methylation, an epigenetic mark …
Disruption to NKCC1 impairs the response of myelinating Schwann cells to neuronal activity and leads to severe peripheral nerve pathology
L Kegel, KLH Marshall-Phelps, M Baraban… - BioRxiv, 2019 - biorxiv.org
Myelinating Schwann cells of the peripheral nervous system (PNS) express numerous ion
channels and transporters, and have the capacity to respond to neuronal activity. However, it …
channels and transporters, and have the capacity to respond to neuronal activity. However, it …
[HTML][HTML] Fear conditioning-related changes in cerebellar Purkinje cell activities in goldfish
M Yoshida, H Kondo - Behavioral and Brain Functions, 2012 - Springer
Background Fear conditioning-induced changes in cerebellar Purkinje cell responses to a
conditioned stimulus have been reported in rabbits. It has been suggested that synaptic long-…
conditioned stimulus have been reported in rabbits. It has been suggested that synaptic long-…