User profiles for Kaushik Panda
 | Kaushik PandaResearch Scientist, Donald Danforth Plant Science Center Verified email at danforthcenter.org Cited by 1149 |
The initiation of epigenetic silencing of active transposable elements is triggered by RDR6 and 21-22 nucleotide small interfering RNAs
Transposable elements ( TEs ) are mobile fragments of DNA that are repressed in both
plant and animal genomes through the epigenetic inheritance of repressed chromatin and …
plant and animal genomes through the epigenetic inheritance of repressed chromatin and …
ARGONAUTE 6 bridges transposable element m RNA‐derived si RNA s to the establishment of DNA methylation
Transposable elements ( TE s) generate mutations and chromosomal instability when active.
To repress TE activity, eukaryotic cells evolved mechanisms to both degrade TE mRNA s …
To repress TE activity, eukaryotic cells evolved mechanisms to both degrade TE mRNA s …
Silencing in sperm cells is directed by RNA movement from the surrounding nurse cell
Plant small interfering RNAs (siRNAs) communicate from cell to cell and travel long
distances through the vasculature. However, siRNA movement into germ cells has remained …
distances through the vasculature. However, siRNA movement into germ cells has remained …
[HTML][HTML] Full-length autonomous transposable elements are preferentially targeted by expression-dependent forms of RNA-directed DNA methylation
Background Chromatin modifications such as DNA methylation are targeted to transposable
elements by small RNAs in a process termed RNA-directed DNA methylation (RdDM). In …
elements by small RNAs in a process termed RNA-directed DNA methylation (RdDM). In …
[HTML][HTML] An siRNA-guided ARGONAUTE protein directs RNA polymerase V to initiate DNA methylation
MJ Sigman, K Panda, R Kirchner, LL McLain, H Payne… - Nature Plants, 2021 - nature.com
In mammals and plants, cytosine DNA methylation is essential for the epigenetic repression
of transposable elements and foreign DNA. In plants, DNA methylation is guided by small …
of transposable elements and foreign DNA. In plants, DNA methylation is guided by small …
The plant response to high CO2 levels is heritable and orchestrated by DNA methylation
Plant responses to abiotic environmental challenges are known to have lasting effects on the
plant beyond the initial stress exposure. Some of these lasting effects are transgenerational…
plant beyond the initial stress exposure. Some of these lasting effects are transgenerational…
Long-read cDNA sequencing enables a “gene-like” transcript annotation of transposable elements
K Panda, RK Slotkin - Plant Cell, 2020 - academic.oup.com
Transcript-based annotations of genes facilitate both genome-wide analyses and detailed
single-locus research. In contrast, transposable element (TE) annotations are rudimentary, …
single-locus research. In contrast, transposable element (TE) annotations are rudimentary, …
[HTML][HTML] High expression in maize pollen correlates with genetic contributions to pollen fitness as well as with coordinated transcription from neighboring transposable …
In flowering plants, gene expression in the haploid male gametophyte (pollen) is essential
for sperm delivery and double fertilization. Pollen also undergoes dynamic epigenetic …
for sperm delivery and double fertilization. Pollen also undergoes dynamic epigenetic …
Arabidopsis RNA Polymerase IV generates 21–22 nucleotide small RNAs that can participate in RNA-directed DNA methylation and may regulate genes
The plant-specific RNA Polymerase IV (Pol IV) transcribes heterochromatic regions,
including many transposable elements (TEs), with the well-described role of generating 24 …
including many transposable elements (TEs), with the well-described role of generating 24 …
Proposed mechanism for the initiation of transposable element silencing by the RDR6-directed DNA methylation pathway
K Panda, RK Slotkin - Plant signaling & behavior, 2013 - Taylor & Francis
The activity of transposable elements is epigenetically suppressed by both transcriptional
and post-transcriptional mechanisms. We recently identified a direct connection between the …
and post-transcriptional mechanisms. We recently identified a direct connection between the …