User profiles for Kaustubh Adhikari

Kaustubh Adhikari

Lecturer in Statistics, the Open University
Verified email at ucl.ac.uk
Cited by 2141

[HTML][HTML] A genome-wide association scan implicates DCHS2, RUNX2, GLI3, PAX1 and EDAR in human facial variation

K Adhikari, M Fuentes-Guajardo… - Nature …, 2016 - nature.com
We report a genome-wide association scan for facial features in ∼6,000 Latin Americans.
We evaluated 14 traits on an ordinal scale and found significant association (P values<5 × 10 …

[HTML][HTML] Admixture in Latin America: geographic structure, phenotypic diversity and self-perception of ancestry based on 7,342 individuals

A Ruiz-Linares, K Adhikari, V Acuña-Alonzo… - PLoS …, 2014 - journals.plos.org
The current genetic makeup of Latin America has been shaped by a history of extensive
admixture between Africans, Europeans and Native Americans, a process taking place within …

[HTML][HTML] A GWAS in Latin Americans highlights the convergent evolution of lighter skin pigmentation in Eurasia

K Adhikari, J Mendoza-Revilla, A Sohail… - Nature …, 2019 - nature.com
We report a genome-wide association scan in >6,000 Latin Americans for pigmentation of
skin and eyes. We found eighteen signals of association at twelve genomic regions. These …

[HTML][HTML] A genome-wide association scan in admixed Latin Americans identifies loci influencing facial and scalp hair features

K Adhikari, T Fontanil, S Cal, J Mendoza-Revilla… - Nature …, 2016 - nature.com
We report a genome-wide association scan in over 6,000 Latin Americans for features of
scalp hair (shape, colour, greying, balding) and facial hair (beard thickness, monobrow, …

[HTML][HTML] Latin Americans show wide-spread Converso ancestry and imprint of local Native ancestry on physical appearance

JC Chacón-Duque, K Adhikari… - Nature …, 2018 - nature.com
Historical records and genetic analyses indicate that Latin Americans trace their ancestry
mainly to the intermixing (admixture) of Native Americans, Europeans and Sub-Saharan …

[HTML][HTML] A genome-wide association study identifies multiple loci for variation in human ear morphology

K Adhikari, G Reales, AJP Smith, E Konka… - Nature …, 2015 - nature.com
Here we report a genome-wide association study for non-pathological pinna morphology in
over 5,000 Latin Americans. We find genome-wide significant association at seven genomic …

The genetic diversity of the Americas

K Adhikari, JC Chacón-Duque… - Annual review of …, 2017 - annualreviews.org
The history of the Americas involved the encounter of millions of Native Americans, Europeans,
and Africans. A variable admixture of these three continental groups has taken place …

Admixture in latin america

K Adhikari, J Mendoza-Revilla… - Current opinion in …, 2016 - Elsevier
Latin Americans arguably represent the largest recently admixed populations in the world.
This reflects a history of massive settlement by immigrants (mostly Europeans and Africans) …

[PDF][PDF] NNT mediates redox-dependent pigmentation via a UVB-and MITF-independent mechanism

J Allouche, I Rachmin, K Adhikari, LM Pardo, JH Lee… - Cell, 2021 - cell.com
Ultraviolet (UV) light and incompletely understood genetic and epigenetic variations determine
skin color. Here we describe an UV- and microphthalmia-associated transcription factor (…

A GWAS in Latin Americans identifies novel face shape loci, implicating VPS13B and a Denisovan introgressed region in facial variation

…, L Duplomb, B Yalcin, J Cotney, K Adhikari… - Science …, 2021 - science.org
To characterize the genetic basis of facial features in Latin Americans, we performed a
genome-wide association study (GWAS) of more than 6000 individuals using 59 landmark-based …