User profiles for Kayla G Barnes
 | Kayla BarnesLiverpool School of Tropical Medicine Verified email at lstmed.ac.uk Cited by 3921 |
Field-deployable viral diagnostics using CRISPR-Cas13
Mitigating global infectious disease requires diagnostic tools that are sensitive, specific, and
rapidly field deployable. In this study, we demonstrate that the Cas13-based SHERLOCK (…
rapidly field deployable. In this study, we demonstrate that the Cas13-based SHERLOCK (…
Zika virus evolution and spread in the Americas
Although the recent Zika virus (ZIKV) epidemic in the Americas and its link to birth defects
have attracted a great deal of attention 1 , 2 , much remains unknown about ZIKV disease …
have attracted a great deal of attention 1 , 2 , much remains unknown about ZIKV disease …
Genomic epidemiology reveals multiple introductions of Zika virus into the United States
Zika virus (ZIKV) is causing an unprecedented epidemic linked to severe congenital abnormalities
1 , 2 . In July 2016, mosquito-borne ZIKV transmission was reported in the continental …
1 , 2 . In July 2016, mosquito-borne ZIKV transmission was reported in the continental …
Directionally selected cytochrome P450 alleles are driving the spread of pyrethroid resistance in the major malaria vector Anopheles funestus
…, H Irving, M Ndula, KG Barnes… - Proceedings of the …, 2013 - National Acad Sciences
Pyrethroid insecticides are critical for malaria control in Africa. However, resistance to this
insecticide class in the malaria vector Anopheles funestus is spreading rapidly across Africa, …
insecticide class in the malaria vector Anopheles funestus is spreading rapidly across Africa, …
[HTML][HTML] Deployable CRISPR-Cas13a diagnostic tools to detect and report Ebola and Lassa virus cases in real-time
Recent outbreaks of viral hemorrhagic fevers (VHFs), including Ebola virus disease (EVD)
and Lassa fever (LF), highlight the urgent need for sensitive, deployable tests to diagnose …
and Lassa fever (LF), highlight the urgent need for sensitive, deployable tests to diagnose …
[HTML][HTML] Genomic analysis of Lassa virus during an increase in cases in Nigeria in 2018
During 2018, an unusual increase in Lassa fever cases occurred in Nigeria, raising concern
among national and international public health agencies. We analyzed 220 Lassa virus …
among national and international public health agencies. We analyzed 220 Lassa virus …
Impact of pyrethroid resistance on operational malaria control in Malawi
The impact of insecticide resistance on insect-borne disease programs is difficult to quantify.
The possibility of eliminating malaria in high-transmission settings is heavily dependent on …
The possibility of eliminating malaria in high-transmission settings is heavily dependent on …
[HTML][HTML] Widespread Pyrethroid and DDT Resistance in the Major Malaria Vector Anopheles funestus in East Africa Is Driven by Metabolic Resistance Mechanisms
Background Establishing the extent, geographical distribution and mechanisms of insecticide
resistance in malaria vectors is a prerequisite for resistance management. Here, we report …
resistance in malaria vectors is a prerequisite for resistance management. Here, we report …
[HTML][HTML] Rise of multiple insecticide resistance in Anopheles funestus in Malawi: a major concern for malaria vector control
JM Riveron, M Chiumia, BD Menze, KG Barnes… - Malaria journal, 2015 - Springer
Background Deciphering the dynamics and evolution of insecticide resistance in malaria
vectors is crucial for successful vector control. This study reports an increase of resistance …
vectors is crucial for successful vector control. This study reports an increase of resistance …
[PDF][PDF] Single-cell profiling of Ebola virus disease in vivo reveals viral and host dynamics
Ebola virus (EBOV) causes epidemics with high mortality yet remains understudied due to
the challenge of experimentation in high-containment and outbreak settings. Here, we used …
the challenge of experimentation in high-containment and outbreak settings. Here, we used …