MicroRNAs (miRNAs) are short non-coding RNAs with key roles in cellular regulation. As part
of the fifth edition of the Functional Annotation of Mammalian Genome (FANTOM5) project, …

Long noncoding RNAs (lncRNAs) constitute the majority of transcripts in the mammalian
genomes, and yet, their functions remain largely unknown. As part of the FANTOM6 project, we …

Within the scope of the FANTOM6 consortium, we perform a large-scale knockdown of 200
long non-coding RNAs (lncRNAs) in human induced pluripotent stem cells (iPSCs) and …

The gene hns of Escherichia coli K-12, which encodes the histone-like protein H-NS, was
inactivated by insertion of a DNA (gene hph) encoding hygromycin phosphotransferase. The …

Intracellular energy balance is important for cell survival. In eukaryotic cells, the most energy-consuming
process is ribosome biosynthesis, which adapts to changes in intracellular …

Long noncoding RNAs (lncRNAs) have emerged as key coordinators of biological and
cellular processes. Characterizing lncRNA expression across cells and tissues is key to …

Induction of supercoiling in plasmid DNA by HU heterotypic and homotypic dimers, a mutant
HU-2 (HupAN12), HBs and HB1 proteins with different DNA-binding affinities was …

DNA demethylation plays a critical role in transcriptional regulation in differentiated somatic
cells. However, there is no experimental evidence that CpG methylation in a small region of …

The 3’ untranslated region (3’UTR) plays a crucial role in determining mRNA stability,
localisation, translation and degradation. Cap analysis gene expression (CAGE), a method for the …

Integration host factor (IHF) is known to be required for the expression of early genes and
formation of the transpososome of mutator phage Mu. Prophage Mucts62 was stably …