It is now evident from studies of mice unable to secrete IgM that both non-immune “natural”
and antigen-induced “immune” IgM are important for protection against pathogens and for …

Cell surface Fc receptor for IgM antibody (FcμR) is the most recently identified member
among FcRs. We determined the cellular distribution of mouse FcμR and the functional …

Background Patients with chronic lymphocytic leukemia (CLL) have reduced seroconversion
rates and lower binding antibody (Ab) and neutralizing antibody (NAb) titers than healthy …

Convalescent plasma (CP) is widely used to treat COVID-19, but without formal evidence of
efficacy. Here, we report the beneficial effects of CP in a severely ill COVID-19 patient with …

CD4+ T cells from alpha beta-T-cell receptor transgenic mice were analyzed for
coexpression of cytokine mRNAs during phenotype development using a double-label in situ …

The vast array of epitopes presented by allografts and the diversity of T cells responding to
them complicates mechanistic studies of rejection. To minimize these problems, we …

Lang et al. have recently published that innate immune cells, including bone-marrow
granulocytes and splenic macrophages, express the plasma-membrane protein Toso as a unique …

無菌 (GF) ニワトリおよび通常の環境で飼育した (CV) ニワトリのリンパ系臓器 (盲腸扁桃, 脾臓,
ファブリシウス嚢, 胸腺) での B および T リンパ球の組織分布を, 各種モノクローナル抗体を用いて免疫…

IgM exists as both a monomer on the surface of B cells and a pentamer secreted by plasma
cells. Both pre-immune “natural” and antigen-induced “immune” IgM antibodies are …

Quantification of the anti-SARS-CoV-2 antibody response has proven to be a prominent
diagnostic tool during the COVID-19 pandemic. Antibody measurements have aided in the …