The polycomb repressive complexes 1 and 2 (PRCs; PRC1 and PRC2) are conserved
histone‐modifying enzymes that often function cooperatively to repress gene expression. The …

Long noncoding RNAs (lncRNAs) cause Polycomb repressive complexes (PRCs) to spread
over broad regions of the mammalian genome. We report that in mouse trophoblast stem …

We describe the development and application of a novel series of vectors that facilitate
CRISPR-Cas9-mediated genome editing in mammalian cells, which we call CRISPR-Bac. …

Quiescence is a reversible G 0 state essential for differentiation, regeneration, stem-cell
renewal, and immune cell activation. Necessary for long-term survival, quiescent chromatin is …

Whether or not a cell chooses to divide is a tightly regulated and extremely important
decision. Cells from yeast to human are able to reversibly exit the cell cycle in response to …

Youth obesity has increased dramatically in the United States, disproportionally affecting
Hawaiian populations. The primary research objective was to describe the influence of parent …

Arylpyran pseudoacids showed slow ring-opening to the oxocarboxylic acids, and fast ring-closure
to the lactols (pseudoacids) in a process that amounts to racemization. Compounds …

… LONG NON-CODING RNAS Aki Keean Braceros A dissertation submitted to the faculty at
t … The original citation is as follows: Braceros et al. “Proximity-dependent recruitment of …

600 – T cells Page 1 AURORA 1 baseline for UPCR included terms for baseline covariate,
treatment, visit and treatment by visit interaction. Interim analysis of AURORA 2 patients …

The purpose of this study was to determine which test is best for predicting adverse
outcomes in pregnancies complicated by diabetes: the nonstress test, biophysical profile, or …