Abstract Characterization of the genetic landscape of Alzheimer’s disease (AD) and related
dementias (ADD) provides a unique opportunity for a better understanding of the associated …

Context Attention-deficit/hyperactivity disorder (ADHD) is a common heritable childhood
behavioral disorder. Identifying risk factors for ADHD may lead to improved intervention and …

Recently, we reported oligoadenylate synthetase 1 (OAS1) contributed to the risk of Alzheimer’s
disease, by its enrichment in transcriptional networks expressed by microglia. However, …

BACKGROUND: Fatty acids, in particular omega-3 fatty acids, have been found to affect
behavior and cognition both directly and indirectly. Evidence to suggest a link with attention-…

Human DNA methylation data have been used to develop biomarkers of ageing, referred to
as ‘epigenetic clocks’, which have been widely used to identify differences between …

Alzheimer’s disease (AD) is a chronic neurodegenerative disease characterized by the
progressive accumulation of amyloid-beta and neurofibrillary tangles of tau in the neocortex. We …

Oxytocin (OXT) has been hypothesized to play a role in aetiology of autism based on a
demonstrated involvement in the regulation of social behaviours. It is postulated that OXT …

Deciphering the genetic landscape of Alzheimer’s disease (AD) is essential to define the
pathophysiological pathways involved and to successfully translate genomics to potential …

Mild-cognitive impairment (MCI) occurs in up to one-fifth of individuals over the age of 65,
with approximately a third of MCI individuals converting to dementia in later life. There is a …

Objective: The primary purpose of this study was to confirm the association of a specific
haplotype of the dopamine transporter gene and attention deficit hyperactivity disorder (ADHD), …