Odor signals are conveyed from the olfactory bulb to the olfactory cortex (OC) by mitral cells (MCs)
and tufted cells (TCs). However, whether and how the two types of projection neuron …

Accumulating evidence points to cortical oscillations as a mechanism for mediating interactions
among functionally specialized neurons in distributed brain circuits 1 , 2 , 3 , 4 , 5 , 6 . A …

The olfactory bulb (OB) is the first relay station of the central olfactory system in the mammalian
brain and contains a few thousand glomeruli on its surface. Because individual glomeruli …

In the past decade, much has been elucidated regarding the functional organization of the
axonal connection of olfactory sensory neurons to olfactory bulb (OB) glomeruli. However, the …

The entorhinal cortex (EC) is the brain region that often exhibits the earliest histological
alterations in Alzheimer's disease (AD), including the formation of neurofibrillary tangles and cell …

Mounting evidence shows that dopamine in the striatum is critically involved in reward-based
reinforcement learning 1 , 2 . However, it remains unclear how dopamine reward signals …

Patients with Alzheimer's disease (AD) suffer from spatial memory impairment and wandering
behavior, but the brain circuit mechanisms causing such symptoms remain largely unclear. …

We asked whether the structural heterogeneity of the hippocampal CA3-CA2 axis is reflected
in how space is mapped onto place cells in CA3-CA2. Place fields were smaller and …

Decades of neuroscience research have shed light on the hippocampus as a key structure for
the formation of episodic memory. The hippocampus is divided into distinct subfields – CA1…

The entorhinal cortex (EC) has bidirectional connections with the hippocampus and plays a
critical role in memory formation and retrieval. EC is one of the most vulnerable regions in …