Aberrant inhibition of programmed cell death (apoptosis) prevents normal homeostasis and
promotes tissue tumorigenesis, but whether it also influences the outcome of common …

Background Attention has long been drawn to the potentially harmful effects of coffee on
health, however recent epidemiological studies have suggested unexpected, possibly …

The reason for the large male predominance in the occurrence of hepatocellular carcinoma (HCC)
remains unknown, and sex hormones may contribute to this phenomenon. We …

Background Laparoscopic low anterior resection for rectal cancer is considered to be more
technically demanding than laparoscopic colectomy. This study aimed to analyze the …

Laparoscopic resection of transverse colon cancer at splenic flexure is technical demanding
and its efficacy remains controversial. The aim of this study was to investigate its technical …

BACKGROUND To identify the role of survivin, a novel inhibitor of apoptosis (IAP) in colorectal
tumorigenesis, the authors investigated tissue expression of survivin in human colorectal …

The overwhelming majority of participants in current genetic studies are of European ancestry.
To elucidate disease biology in the East Asian population, we conducted a genome-wide …

To elucidate the genetics of coronary artery disease (CAD) in the Japanese population, we
conducted a large-scale genome-wide association study of 168,228 individuals of Japanese …

Colorectal cancer is an alcohol-related malignancy; however, the association appears to be
stronger among Asian populations with a relatively high prevalence of the slow-…

PURPOSE: To examine the relation between green tea consumption and arteriographically
determined coronary atherosclerosis. METHODS: Study subjects were 512 patients (302 …