The DREAM complex mediates GIST cell quiescence and is a novel therapeutic target to enhance imatinib-induced apoptosis

…, JL Baron, JP Zewe, A Wozniak, KR Mehalek… - Cancer research, 2013 - AACR
Gastrointestinal stromal tumors (GIST) can be successfully treated with imatinib mesylate (Gleevec);
however, complete remissions are rare and patients frequently achieve disease …

Unbiased compound screening identifies unexpected drug sensitivities and novel treatment options for gastrointestinal stromal tumors

S Boichuk, DJ Lee, KR Mehalek, KR Makielski… - Cancer research, 2014 - AACR
Most gastrointestinal stromal tumors (GIST) are caused by oncogenic KIT or platelet-derived
growth factor receptor activation, and the small molecule kinase inhibitor imatinib mesylate …

[HTML][HTML] Differential antitumor activity of compounds targeting the ubiquitin-proteasome machinery in gastrointestinal stromal tumor (GIST) cells

…, AA Ali, DM Lee, YK Gebreyohannes, KR Mehalek… - Scientific Reports, 2020 - nature.com
The majority of gastrointestinal stromal tumors (GISTs) are driven by oncogenic KIT signaling
and can therefore be effectively treated with the tyrosine kinase inhibitor (TKI) imatinib …

Perinatal outcome after multifetal reduction to twins compared with nonreduced multiple gestations

CA MELGAR, DL ROSENFELD… - Obstetrics & …, 1991 - journals.lww.com
The outcomes of twins resulting from multifetal reduction were analyzed to examine whether
the outcome was improved over that of triplet and quadruplet pregnancies and similar to …

Contemporary outcomes with the latest 1000 cases of multifetal pregnancy reduction (MPR)

…, J Kamrath, J Getrajdman, R Berkowitz… - American journal of …, 2008 - Elsevier
OBJECTIVE: This study was undertaken to report on the outcome of multifetal pregnancy
reduction in the most up-to-date largest single center experience with this procedure, and …

[PDF][PDF] Bloomington High School Wind Symphony and Symphonic Winds, February 16, 2020

ME Chernick, AC Marinello III, P Hash, ZA Taylor - 2020 - ir.library.illinoisstate.edu
ASSISTED LISTENING DEVICES Thank you for joining us for today’s performance of the Illinois
State University Symphonic Winds. We hope that you will enjoy our concert, and that you …

A single center experience with 1000 consecutive cases of multifetal pregnancy reduction

J Stone, K Eddleman, L Lynch, RL Berkowitz - American journal of …, 2002 - Elsevier
Objective: Multifetal pregnancy reduction (MPR) is a technique developed to reduce the risks
of a multifetal pregnancy. The objective of this article was to report the outcome of MPR in …

[PDF][PDF] The Magic Bullet: Cost-Effective Next Generation Cubicin

D Lee - chem.cmu.edu
Daptomycin (trade name: Cubicin), marketed by Cubist Pharmaceuticals, is a novel
lipoprotein antibiotic specific to gram-positive bacteria. It is effective in treating vancomycin-and …

Multifetal pregnancy reduction and selective termination

MC Bush, KA Eddleman - Clinics in perinatology, 2003 - perinatology.theclinics.com
The incidence of multifetal pregnancies has increased markedly over the past 20 years because
of advancements in assisted reproductive techniques. Despite efforts to avoid multifetal …

One hundred consecutive cases of selective termination of an abnormal fetus in a multifetal gestation

RL Berkowitz, JL Stone, KA Eddleman - Obstetrics & Gynecology, 1997 - Elsevier
OBJECTIVE: To determine whether transabdominal selective termination of one or more
abnormal fetuses in a multifetal pregnancy with dichorionic placentation is a safe and effective …