Gallium(III)–Salophen as a Dual Inhibitor of Pseudomonas aeruginosa Heme Sensing and Iron Acquisition
Pseudomonas aeruginosa is an opportunistic bacterium that causes life-threatening infections
in immunocompromised patients. In infection, it uses heme as a primary iron source and …
in immunocompromised patients. In infection, it uses heme as a primary iron source and …
Enhanced silencing and stabilization of siRNA polyplexes by histidine-mediated hydrogen bonds
ST Chou, K Hom, D Zhang, Q Leng, LJ Tricoli… - Biomaterials, 2014 - Elsevier
Branched peptides containing histidines and lysines (HK) have been shown to be effective
carriers for DNA and siRNA. We anticipate that elucidation of the binding mechanism of HK …
carriers for DNA and siRNA. We anticipate that elucidation of the binding mechanism of HK …
Cranberry Xyloglucan Structure and Inhibition of Escherichia coli Adhesion to Epithelial Cells
…, HK Chau, AK White, JPJ Marais, K Hom… - Journal of agricultural …, 2015 - ACS Publications
Cranberry juice has been recognized as a treatment for urinary tract infections on the basis of
scientific reports of proanthocyanidin anti-adhesion activity against Escherichia coli as well …
scientific reports of proanthocyanidin anti-adhesion activity against Escherichia coli as well …
How a Formate Dehydrogenase Responds to Oxygen: Unexpected O2 Insensitivity of an Enzyme Harboring Tungstopterin, Selenocysteine, and [4Fe–4S] Clusters
JE Graham, D Niks, GM Zane, Q Gui, K Hom… - ACS …, 2022 - ACS Publications
The reversible two-electron interconversion of formate and CO 2 is catalyzed by both nonmetallo-
and metallo-formate dehydrogenases (FDHs). The latter group comprises molybdenum…
and metallo-formate dehydrogenases (FDHs). The latter group comprises molybdenum…
Novel noncatalytic substrate-selective p38α-specific MAPK inhibitors with endothelial-stabilizing and anti-inflammatory activity
…, A Brophy, R Martinez, K Hom… - The Journal of …, 2017 - journals.aai.org
The p38 MAPK family is composed of four kinases of which p38α/MAPK14 is the major
proinflammatory member. These kinases contribute to many inflammatory diseases, but the …
proinflammatory member. These kinases contribute to many inflammatory diseases, but the …
Photochemical addition of amino acids and peptides to polyuridylic acid
…, J CARBONE, E STEADY, K HOM - Photochemistry and …, 1984 - Wiley Online Library
The quantum yields for photochemical addition of glycine and the L‐amino acids commonly
occurring in proteins (excluding proline) to polyuridylic acid have been determined in …
occurring in proteins (excluding proline) to polyuridylic acid have been determined in …
Photochemical addition of amino acids and peptides to DNA
…, J CHRISTENSEN, K HOM - Photochemistry and …, 1984 - Wiley Online Library
The quantum yields for photochemical addition of twenty of the amino acids commonly
occurring in proteins to denatured calf thymus DNA have been determined in deoxygenated …
occurring in proteins to denatured calf thymus DNA have been determined in deoxygenated …
NMR metabolomic analysis of caco-2 cell differentiation
IJ Lee, K Hom, G Bai, M Shapiro - Journal of proteome research, 2009 - ACS Publications
The high-resolution 1 H NMR spectra as applied to Caco-2 cells during their differentiation
into enterocyte like cells are presented. The data clearly reveal differences in the metabolic …
into enterocyte like cells are presented. The data clearly reveal differences in the metabolic …
Small Molecule Antivirulents Targeting the Iron-Regulated Heme Oxygenase (HemO) of P. aeruginosa
K Hom, GA Heinzl, S Eakanunkul… - Journal of medicinal …, 2013 - ACS Publications
Bacteria require iron for survival and virulence and employ several mechanisms including
utilization of the host heme containing proteins. The final step in releasing iron is the oxidative …
utilization of the host heme containing proteins. The final step in releasing iron is the oxidative …
Photochemical addition of amino acids and peptides to homopolyribonucleotides of the major DNA bases
MD SHETLAR, K HOM, J CARBONE… - Photochemistry and …, 1984 - Wiley Online Library
The photochemical quantum yields for addition of glycine and the L‐amino acids commonly
occurring in proteins (excluding proline) to polyadenylic acid, polycytidylic acid, polyguanylic …
occurring in proteins (excluding proline) to polyadenylic acid, polycytidylic acid, polyguanylic …