[HTML][HTML] wrmXpress: A modular package for high-throughput image analysis of parasitic and free-living worms
Advances in high-throughput and high-content imaging technologies require concomitant
development of analytical software capable of handling large datasets and generating …
development of analytical software capable of handling large datasets and generating …
[HTML][HTML] Multivariate chemogenomic screening prioritizes new macrofilaricidal leads
Abstract Development of direct acting macrofilaricides for the treatment of human filariases
is hampered by limitations in screening throughput imposed by the parasite life cycle. In vitro …
is hampered by limitations in screening throughput imposed by the parasite life cycle. In vitro …
[HTML][HTML] Spatial transcriptomics reveals antiparasitic targets associated with essential behaviors in the human parasite Brugia malayi
Lymphatic filariasis (LF) is a chronic debilitating neglected tropical disease (NTD) caused by
mosquito-transmitted nematodes that afflicts over 60 million people. Control of LF relies on …
mosquito-transmitted nematodes that afflicts over 60 million people. Control of LF relies on …
Pharmacological profiling of a Brugia malayi muscarinic acetylcholine receptor as a putative antiparasitic target
The diversification of anthelmintic targets and mechanisms of action will help ensure the
sustainable control of nematode infections in response to the growing threat of drug resistance. …
sustainable control of nematode infections in response to the growing threat of drug resistance. …
[PDF][PDF] Multivariate screening of Brugia spp. adults
… Nicolas J. Wheeler University of Wisconsin-Madison https://orcid.org/0000-0002-5909-4190
Kaetlyn T. Ryan … Gallo … Rueden CT, Schindelin J, Hiner MC, DeZonia BE, Walter AE, Arena …
Kaetlyn T. Ryan … Gallo … Rueden CT, Schindelin J, Hiner MC, DeZonia BE, Walter AE, Arena …
Bivariate, high-content screening of Brugia malayi microfilariae
The following protocol is for performing bivariate (motility and viability) phenotypic drug screens
against Brugia spp. microfilariae (mf). It has been heavily optimized for utilization with an …
against Brugia spp. microfilariae (mf). It has been heavily optimized for utilization with an …
Bone marrow transplantation for acute lymphoblastic leukaemia
AJ Barrett, JR Kendra, CF Lucas… - British Journal of …, 1982 - Wiley Online Library
Twenty patients have undergone bone marrow transplantation for acute lymphoblastic
leukaemia (ALL). Eighteen patients were in complete remission and two had <10% leukaemic …
leukaemia (ALL). Eighteen patients were in complete remission and two had <10% leukaemic …
Prediction and prevention of relapse of acute lymphoblastic leukaemia after bone marrow transplantation
AJ Barrett, R Joshi, JR Kendra… - British journal of …, 1986 - Wiley Online Library
Results of bone marrow transplantation (BMT) in 63 adults and children with ALL transplanted
in the 5‐year period 1979–83 were analysed. Twenty‐one patients (33%) relapsed, 25% …
in the 5‐year period 1979–83 were analysed. Twenty‐one patients (33%) relapsed, 25% …
Multiple chronic conditions, resilience, and workforce transitions in later life: A socio-ecological model
Purpose of the Study: Despite the growing prevalence of multiple chronic conditions (MCC),
a problem that disproportionally affects older adults, few studies have examined the impact …
a problem that disproportionally affects older adults, few studies have examined the impact …
Explant vs redo-TAVR after transcatheter valve failure: mid-term outcomes from the EXPLANTORREDO-TAVR international registry
…, K Vitanova, H Ruge, A Unbehaun, J Kempfert… - Cardiovascular …, 2023 - jacc.org
Background Valve reintervention after transcatheter aortic valve replacement (TAVR) failure
has not been studied in detail. Objectives The authors sought to determine outcomes of …
has not been studied in detail. Objectives The authors sought to determine outcomes of …