Similarities in neocortical circuit organization across areas and species suggest a common
strategy to process diverse types of information, including sensation from diverse modalities, …

Vision, choice, action and behavioural engagement arise from neuronal activity that may be
distributed across brain regions. Here we delineate the spatial distribution of neurons …

Simultaneous recording from large numbers of neurons is a prerequisite for understanding
their cooperative behavior. Various recording techniques and spike separation methods are …

Neurons can produce action potentials with high temporal precision 1 . A fundamental issue
is whether, and how, this capability is used in information processing. According to the ‘cell …

Sensory, motor and cognitive operations involve the coordinated action of large neuronal
populations across multiple brain regions in both superficial and deep structures 1 , 2 . Existing …

The brain continuously adapts its processing machinery to behavioural demands. To achieve
this, it rapidly modulates the operating mode of cortical circuits, controlling the way that …

Developments in microfabrication technology have enabled the production of neural electrode
arrays with hundreds of closely spaced recording sites, and electrodes with thousands of …

Cortical neurons show irregular but structured spike trains. This has been interpreted as
evidence for 'temporal coding', whereby stimuli are represented by precise spike-timing patterns…

The mammalian nervous system executes complex behaviors controlled by specialized,
precisely positioned, and interacting cell types. Here, we used RNA sequencing of half a million …

INTRODUCTION Electrode arrays based on complementary metal-oxide semiconductor
silicon fabrication technology, such as Neuropixels probes, have enabled recordings of …