Robustness of cortical topography across fields, laminae, anesthetic states, and neurophysiological signal types

…, AR Chambers, KN Darrow, KE Hancock… - Journal of …, 2012 - Soc Neuroscience
Topographically organized maps of the sensory receptor epithelia are regarded as cornerstones
of cortical organization as well as valuable readouts of diverse biological processes …

A physiologically based model of interaural time difference discrimination

KE Hancock, B Delgutte - Journal of Neuroscience, 2004 - Soc Neuroscience
Interaural time difference (ITD) is a cue to the location of sounds containing low frequencies
and is represented in the inferior colliculus (IC) by cells that respond maximally at a …

The middle ear muscle reflex in the diagnosis of cochlear neuropathy

MD Valero, KE Hancock, MC Liberman - Hearing research, 2016 - Elsevier
Cochlear neuropathy, ie the loss of auditory nerve fibers (ANFs) without loss of hair cells,
may cause hearing deficits without affecting threshold sensitivity, particularly if the subset of …

Middle ear muscle reflex and word recognition in “normal-hearing” adults: evidence for cochlear synaptopathy?

AM Mepani, SA Kirk, KE Hancock, K Bennett… - Ear and …, 2020 - journals.lww.com
Objectives: Permanent threshold elevation after noise exposure, ototoxic drugs, or aging is
caused by loss of sensory cells; however, animal studies show that hair cell loss is often …

[HTML][HTML] Sensory overamplification in layer 5 auditory corticofugal projection neurons following cochlear nerve synaptic damage

MM Asokan, RS Williamson, KE Hancock… - Nature …, 2018 - nature.com
Layer 5 (L5) cortical projection neurons innervate far-ranging brain areas to coordinate
integrative sensory processing and adaptive behaviors. Here, we characterize a plasticity in L5 …

Effects of cochlear synaptopathy on middle-ear muscle reflexes in unanesthetized mice

MD Valero, KE Hancock, SF Maison, MC Liberman - Hearing research, 2018 - Elsevier
Cochlear synaptopathy, ie the loss of auditory-nerve connections with cochlear hair cells, is
seen in aging, noise damage, and other types of acquired sensorineural hearing loss. …

[PDF][PDF] Locomotion and task demands differentially modulate thalamic audiovisual processing during active search

RS Williamson, KE Hancock, BG Shinn-Cunningham… - Current Biology, 2015 - cell.com
Active search is a ubiquitous goal-driven behavior wherein organisms purposefully investigate
the sensory environment to locate a target object. During active search, brain circuits …

Bottom-up and top-down neural signatures of disordered multi-talker speech perception in adults with normal hearing

A Parthasarathy, KE Hancock, K Bennett, V DeGruttola… - Elife, 2020 - elifesciences.org
In social settings, speech waveforms from nearby speakers mix together in our ear canals.
Normally, the brain unmixes the attended speech stream from the chorus of background …

Cellular and widefield imaging of sound frequency organization in primary and higher order fields of the mouse auditory cortex

…, J Resnik, RS Williamson, KE Hancock… - Cerebral …, 2020 - academic.oup.com
The mouse auditory cortex (ACtx) contains two core fields—primary auditory cortex (A1) and
anterior auditory field (AAF)—arranged in a mirror reversal tonotopic gradient. The best …

Neural coding of interaural time differences with bilateral cochlear implants: effects of congenital deafness

KE Hancock, V Noel, DK Ryugo… - Journal of …, 2010 - Soc Neuroscience
Human bilateral cochlear implant users do poorly on tasks involving interaural time
differences (ITD), a cue that provides important benefits to the normal hearing, especially in …