The fly Drosophila melanogaster is one of the most intensively studied organisms in biology
and serves as a model system for the investigation of many developmental and cellular …

Drosophila melanogaster is one of the most well studied genetic model organisms; nonetheless,
its genome still contains unannotated coding and non-coding genes, transcripts, exons …

To gain insight into how genomic information is translated into cellular and developmental
programs, the Drosophila model organism Encyclopedia of DNA Elements (modENCODE) …

We demonstrate the feasibility of generating thousands of transgenic Drosophila melanogaster
lines in which the expression of an exogenous gene is reproducibly directed to distinct …

Animal transcriptomes are dynamic, with each cell type, tissue and organ system expressing
an ensemble of transcript isoforms that give rise to substantial diversity. Here we have …

Determining the composition of protein complexes is an essential step toward understanding
the cell as an integrated system. Using coaffinity purification coupled to mass spectrometry …

We constructed Drosophila melanogaster bacterial artificial chromosome libraries with 21-kilobase
and 83-kilobase inserts in the P[acman] system. We mapped clones representing 12-…

Drosophila melanogaster plays an important role in molecular, genetic, and genomic studies
of heredity, development, metabolism, behavior, and human disease. The initial reference …

Genome sequences for most metazoans and plants are incomplete because of the presence
of repeated DNA in the heterochromatin. The heterochromatic regions of Drosophila …

The transcriptome is the readout of the genome. Identifying common features in it across distant
species can reveal fundamental principles. To this end, the ENCODE and modENCODE …