Microfluidic technologies for yeast replicative lifespan studies
KL Chen, MM Crane, M Kaeberlein - Mechanisms of ageing and …, 2017 - Elsevier
The budding yeast Saccharomyces cerevisiae has been used as a model organism for the
study of aging for over 50 years. In this time, the canonical aging experiment—replicative …
study of aging for over 50 years. In this time, the canonical aging experiment—replicative …
Trajectories of aging: how systems biology in yeast can illuminate mechanisms of personalized aging
MM Crane, KL Chen, BW Blue, M Kaeberlein - Proteomics, 2020 - Wiley Online Library
All organisms age, but the extent to which all organisms age the same way remains a
fundamental unanswered question in biology. Across species, it is now clear that at least some …
fundamental unanswered question in biology. Across species, it is now clear that at least some …
Disposable masks release microplastics to the aqueous environment with exacerbation by natural weathering
The COVID-19 pandemic has driven explosive growth in the use of masks has resulted in
many issues related to the disposal and management of waste masks. As improperly disposed …
many issues related to the disposal and management of waste masks. As improperly disposed …
Molecular structure of human KATP in complex with ATP and ADP
KPK Lee, J Chen, R MacKinnon - Elife, 2017 - elifesciences.org
10.7554/eLife.32481.001 In many excitable cells, KATP channels respond to intracellular
adenosine nucleotides: ATP inhibits while ADP activates. We present two structures of the …
adenosine nucleotides: ATP inhibits while ADP activates. We present two structures of the …
In vivo diagnosis of oral dysplasia and malignancy using optical coherence tomography: preliminary studies in 50 patients
Background In vivo, non‐invasive optical coherence tomography (OCT) permits high‐resolution
imaging of tissue surfaces and subsurfaces, with the potential capability for detection …
imaging of tissue surfaces and subsurfaces, with the potential capability for detection …
Marine oil spills—oil pollution, sources and effects
As the major energy source worldwide, petroleum products have been increasingly produced
and consumed, and the environmental impact involved also rises. Despite significant …
and consumed, and the environmental impact involved also rises. Despite significant …
Recent advances in developing cellulosic sorbent materials for oil spill cleanup: A state-of-the-art review
Despite advances in technology and safety measures, accidental releases of crude oil and
refined products into marine and freshwater environments remains a major environmental …
refined products into marine and freshwater environments remains a major environmental …
Activation of fast skeletal muscle troponin as a potential therapeutic approach for treating neuromuscular diseases
…, KH Lee, D Marquez, WF Browne IV, MM Chen… - Nature medicine, 2012 - nature.com
Limited neural input results in muscle weakness in neuromuscular disease because of a
reduction in the density of muscle innervation, the rate of neuromuscular junction activation or …
reduction in the density of muscle innervation, the rate of neuromuscular junction activation or …
Noise-resilient edge modes on a chain of superconducting qubits
…, D Landhuis, P Laptev, KM Lau, J Lee, L Laws… - Science, 2022 - science.org
Inherent symmetry of a quantum system may protect its otherwise fragile states. Leveraging
such protection requires testing its robustness against uncontrolled environmental …
such protection requires testing its robustness against uncontrolled environmental …
RSNA/QIBA: Shear wave speed as a biomarker for liver fibrosis staging
An interlaboratory study of shear wave speed (SWS) estimation was performed. Commercial
shear wave elastography systems from Fibroscan, Philips, Siemens and Supersonic …
shear wave elastography systems from Fibroscan, Philips, Siemens and Supersonic …