Microfluidic technologies for yeast replicative lifespan studies

KL Chen, MM Crane, M Kaeberlein - Mechanisms of ageing and …, 2017 - Elsevier
The budding yeast Saccharomyces cerevisiae has been used as a model organism for the
study of aging for over 50 years. In this time, the canonical aging experiment—replicative …

Trajectories of aging: how systems biology in yeast can illuminate mechanisms of personalized aging

MM Crane, KL Chen, BW Blue, M Kaeberlein - Proteomics, 2020 - Wiley Online Library
All organisms age, but the extent to which all organisms age the same way remains a
fundamental unanswered question in biology. Across species, it is now clear that at least some …

Disposable masks release microplastics to the aqueous environment with exacerbation by natural weathering

Z Wang, C An, X Chen, K Lee, B Zhang… - Journal of hazardous …, 2021 - Elsevier
The COVID-19 pandemic has driven explosive growth in the use of masks has resulted in
many issues related to the disposal and management of waste masks. As improperly disposed …

Molecular structure of human KATP in complex with ATP and ADP

KPK Lee, J Chen, R MacKinnon - Elife, 2017 - elifesciences.org
10.7554/eLife.32481.001 In many excitable cells, KATP channels respond to intracellular
adenosine nucleotides: ATP inhibits while ADP activates. We present two structures of the …

In vivo diagnosis of oral dysplasia and malignancy using optical coherence tomography: preliminary studies in 50 patients

…, S Guo, J Zhang, K Osann, Z Chen… - Lasers in Surgery …, 2009 - Wiley Online Library
Background In vivo, non‐invasive optical coherence tomography (OCT) permits high‐resolution
imaging of tissue surfaces and subsurfaces, with the potential capability for detection …

Marine oil spills—oil pollution, sources and effects

…, EJ Matchinski, B Chen, X Ye, L Jing, K Lee - World seas: an …, 2019 - Elsevier
As the major energy source worldwide, petroleum products have been increasingly produced
and consumed, and the environmental impact involved also rises. Despite significant …

Recent advances in developing cellulosic sorbent materials for oil spill cleanup: A state-of-the-art review

S ben Hammouda, Z Chen, C An, K Lee - Journal of Cleaner Production, 2021 - Elsevier
Despite advances in technology and safety measures, accidental releases of crude oil and
refined products into marine and freshwater environments remains a major environmental …

Activation of fast skeletal muscle troponin as a potential therapeutic approach for treating neuromuscular diseases

…, KH Lee, D Marquez, WF Browne IV, MM Chen… - Nature medicine, 2012 - nature.com
Limited neural input results in muscle weakness in neuromuscular disease because of a
reduction in the density of muscle innervation, the rate of neuromuscular junction activation or …

Noise-resilient edge modes on a chain of superconducting qubits

…, D Landhuis, P Laptev, KM Lau, J Lee, L Laws… - Science, 2022 - science.org
Inherent symmetry of a quantum system may protect its otherwise fragile states. Leveraging
such protection requires testing its robustness against uncontrolled environmental …

RSNA/QIBA: Shear wave speed as a biomarker for liver fibrosis staging

…, M Bernal, J Brum, HW Chan, S Chen… - 2013 IEEE …, 2013 - ieeexplore.ieee.org
An interlaboratory study of shear wave speed (SWS) estimation was performed. Commercial
shear wave elastography systems from Fibroscan, Philips, Siemens and Supersonic …