A role for cell sex in stem cell–mediated skeletal muscle regeneration: female cells have higher muscle regeneration efficiency

…, RC Schugar, JB Pollett, B Sun, KL Urish… - The Journal of cell …, 2007 - rupress.org
We have shown that muscle-derived stem cells (MDSCs) transplanted into dystrophic (mdx)
mice efficiently regenerate skeletal muscle. However, MDSC populations exhibit …

Staphylococcus aureus osteomyelitis: bone, bugs, and surgery

KL Urish, JE Cassat - Infection and immunity, 2020 - Am Soc Microbiol
Osteomyelitis, or inflammation of bone, is most commonly caused by invasion of bacterial
pathogens into the skeleton. Bacterial osteomyelitis is notoriously difficult to treat, in part …

Artificial intelligence and orthopaedics: an introduction for clinicians

TG Myers, PN Ramkumar, BF Ricciardi, KL Urish… - JBJS, 2020 - journals.lww.com
… MD 1 ; Urish, Kenneth L. MD, PhD 3 ; Kipper, Jens PhD 4 ; Ketonis, Constantinos MD,
PhD 1 … Reznik AM, Urish KL. Understanding the impact of artificial intelligence on …

[HTML][HTML] Differential myocardial infarct repair with muscle stem cells compared to myoblasts

H Oshima, TR Payne, KL Urish, T Sakai, Y Ling… - Molecular Therapy, 2005 - cell.com
Myoblast transplantation for cardiac repair has generated beneficial results in both animals
and humans; however, poor viability and poor engraftment of myoblasts after implantation in …

A multicenter study of irrigation and debridement in total knee arthroplasty periprosthetic joint infection: treatment failure is high

KL Urish, AG Bullock, AM Kreger, NB Shah… - The Journal of …, 2018 - Elsevier
… Author links open overlay panel Kenneth L. Urish MD, PhD a b c d e , Andrew G. Bullock …
Dr Kenneth Urish is supported in part by the National Institute of Arthritis and Musculoskeletal …

Predicting early symptomatic osteoarthritis in the human knee using machine learning classification of magnetic resonance images from the osteoarthritis initiative

…, CE Coletta, B Lehallier, KL Urish… - Journal of …, 2017 - Wiley Online Library
The purpose of this study is to evaluate the ability of a machine learning algorithm to classify
in vivo magnetic resonance images (MRI) of human articular cartilage for development of …

[HTML][HTML] Antibiotic-tolerant Staphylococcus aureus Biofilm Persists on Arthroplasty Materials

KL Urish, PW DeMuth, BW Kwan, DW Craft… - … and Related Research®, 2016 - Springer
Background The continued presence of biofilm may be one cause of the high risk of failure
observed with irrigation and débridement with component retention in acute periprosthetic …

The toxin-antitoxin MazEF drives Staphylococcus aureus biofilm formation, antibiotic tolerance, and chronic infection

…, RMQ Shanks, AR Richardson, KL Urish - MBio, 2019 - Am Soc Microbiol
Staphylococcus aureus is the major organism responsible for surgical implant infections.
Antimicrobial treatment of these infections often fails, leading to expensive surgical intervention …

Antioxidant levels represent a major determinant in the regenerative capacity of muscle stem cells

KL Urish, JB Vella, M Okada, BM Deasy… - Molecular biology of …, 2009 - Am Soc Cell Biol
Stem cells are classically defined by their multipotent, long-term proliferation, and self-renewal
capabilities. Here, we show that increased antioxidant capacity represents an additional …

Large variations in clinical antibiotic activity against Staphylococcus aureus biofilms of periprosthetic joint infection isolates

…, D Ma, DD Bonar, N Shah, KL Urish - Journal of …, 2019 - Wiley Online Library
Staphylococcus aureus biofilms have a high tolerance to antibiotics, making the treatment of
periprosthetic joint infection (PJI) challenging. From a clinical perspective, bacteria from …