Objectives: To analyze alveolar dynamics in healthy and acid-injured lungs of ventilated
mice. Protective ventilation is potentially lifesaving in patients with acute lung injury. However, …

Microphysiological systems play a pivotal role in progressing toward a global paradigm shift
in drug development. Here, we designed a four-organ-chip interconnecting miniaturized …

Antibody therapies targeting the epithelial growth factor receptor (EGFR) are being
increasingly applied in cancer therapy. However, increased tumour containment correlates …

The dynamics of blood flow in the smallest vessels and passages of the human body, where
the cellular character of blood becomes prominent, plays a dominant role in the transport …

Alveolar recruitment is a central strategy in the ventilation of patients with acute lung injury
and other lung diseases associated with alveolar collapse and atelectasis. However, …

The placenta is a vital interface between the mother and her developing fetus. Micro-haemodynamics
of the placenta, where the particulate nature of blood flow cannot be ignored, …

We report observations of the self-assembly of coated droplets into regular clusters at the
sudden expansion of a microfluidic channel. A double emulsion consisting of a regular train of …

Microphysiological systems are fundamental for progressing towards a global paradigm
shift in drug development through the generation of patient-on-a-chip models. An increasing …

Intravital microscopy (IVM) is a well-established imaging technique for real-time monitoring
of microscale lung tissue dynamics. Although accepted as a gold standard in respiratory …

Microcapsules with liquid cores encapsulated by thin membranes have many applications
in science, medicine and industry. In this paper, we design a suspension of microcapsules …