User profiles for Kesavan Manickam

Kesavan Manickam

Scientist, Pharmacology and toxicology
Verified email at icar.gov.in
Cited by 1168

[HTML][HTML] Drug repurposing approach to fight COVID-19

TU Singh, S Parida, MC Lingaraju, M Kesavan… - Pharmacological …, 2020 - Springer
Currently, there are no treatment options available for the deadly contagious disease,
coronavirus disease 2019 (COVID-19). Drug repurposing is a process of identifying new uses for …

[PDF][PDF] Essential oils as a feed additive in poultry nutrition

…, P Tamilmahan, M Kesavan… - Adv. Anim …, 2014 - nexusacademicpublishers.com
The dietary use of antibiotics has been practised for decades in animal production especially
in commercial poultry production as a growth promoter. The need for the use of antibiotics …

Oral nanoparticulate curcumin combating arsenic-induced oxidative damage in kidney and brain of rats

…, V Karunakaran, S Suresh, M Kesavan - Toxicology and …, 2016 - journals.sagepub.com
Arsenic exposure through drinking water causes oxidative stress and tissue damage in the
kidney and brain. Curcumin (CUR) is a good antioxidant with limited clinical application …

Nanocurcumin ameliorates Staphylococcus aureus-induced mastitis in mouse by suppressing NF‑κB signaling and inflammation

S Suresh, P Sankar, AG Telang, M Kesavan… - International …, 2018 - Elsevier
Mastitis is the inflammation of the mammary glands caused by bacteria. It causes severe
economic loss to dairy industry. Curcumin, a polyphenol obtained from turmeric, has …

Economic importance of ticks and their effective control strategies

HV Manjunathachar, BC Saravanan, M Kesavan… - Asian Pacific Journal of …, 2014 - Elsevier
Role of livestock in improvement of a country's economy is inevitable. Livestock contributes
a lion's share in agricultural sector of developing countries. Several developing countries …

Atorvastatin restores arsenic-induced vascular dysfunction in rats: modulation of nitric oxide signaling and inflammatory mediators

M Kesavan, TS Sarath, K Kannan, S Suresh… - Toxicology and applied …, 2014 - Elsevier
We evaluated whether atorvastatin, an extensively prescribed statin for reducing the risks of
cardiovascular diseases, can reduce the risk of arsenic-induced vascular dysfunction and …

Immunomodulatory effects of nanocurcumin in arsenic-exposed rats

P Sankar, AG Telang, S Suresh, M Kesavan… - International …, 2013 - Elsevier
We evaluated whether the nanoformulation of curcumin could be more effective than free
curcumin against arsenic-induced immune dysfunction in rats. Curcumin was encapsulated in …

Impact of heat stress on broilers with varying body weights: Elucidating their interactive role through physiological signatures

…, G Kolluri, JS Tyagi, G Marappan, K Manickam… - Journal of Thermal …, 2021 - Elsevier
Physiological determinants of different body weight (BW) broiler chickens under heat
stressed conditions were investigated to compare the performance at market age considering …

Protective action of curcumin and nano-curcumin against arsenic-induced genotoxicity in rats in vivo

…, K Ramya, K Vijayakaran, M Kesavan… - Molecular biology …, 2014 - Springer
We explored whether nanoformulation of curcumin can cause better protective effect than
free curcumin against arsenic-induced genotoxicity. Curcumin-loaded Poly(lactic-co-glycolic …

Metabolism of aceclofenac to diclofenac in the domestic water buffalo Bubalus bubalis confirms it as a threat to Critically Endangered Gyps vultures in South Asia

…, V Naidoo, K Mahendran, M Kesavan… - Environmental …, 2022 - Elsevier
Vulture declines in South Asia were caused by accidental poisoning by the veterinary non-steroidal
anti-inflammatory drug (NSAID) diclofenac. Although veterinary use of diclofenac …