User profiles for Kevin Howland
 | K HowlandSchool of Biosciences, University of Kent Verified email at sky.com Cited by 2324 |
Cytotoxic T lymphocytes recognize a fragment of influenza virus matrix protein in association with HLA-A2
F Gotch, J Rothbard, K Howland, A Townsend… - Nature, 1987 - nature.com
Both human and murine cytotoxic T cells (CTL) elicited in response to infection with influenza
A viruses have been shown to be specific for internal viral proteins, such as the matrix and …
A viruses have been shown to be specific for internal viral proteins, such as the matrix and …
[HTML][HTML] The effect of caffeine on cognitive performance is influenced by CYP1A2 but not ADORA2A genotype, yet neither genotype affects exercise performance in …
Purpose To determine the influence of two commonly occurring genetic polymorphisms on
exercise, cognitive performance, and caffeine metabolism, after caffeine ingestion. Methods …
exercise, cognitive performance, and caffeine metabolism, after caffeine ingestion. Methods …
[HTML][HTML] A novel HPLC method for the concurrent analysis and quantitation of seven water-soluble vitamins in biological fluids (plasma and urine): a validation study …
M Grotzkyj Giorgi, K Howland, C Martin… - The Scientific World …, 2012 - hindawi.com
An HPLC method was developed and validated for the concurrent detection and quantitation
of seven water-soluble vitamins (C, B 1 , B 2 , B 5 , B 6 , B 9 , B 12 ) in biological matrices (…
of seven water-soluble vitamins (C, B 1 , B 2 , B 5 , B 6 , B 9 , B 12 ) in biological matrices (…
Structural model of HLA-DR1 restricted T cell antigen recognition
JB Rothbard, RI Lechler, K Howland, V Bal, DD Eckels… - Cell, 1988 - cell.com
Two human helper T cell determinants in influenza have been identified, one in the hemagglutinin
and the other in the matrix protein (Mt). Both were shown to be DRl restricted by using …
and the other in the matrix protein (Mt). Both were shown to be DRl restricted by using …
Degenerate binding of immunogenic peptides to HLA-DR proteins on B cell surfaces
Binding of linear fragments of protein antigens to class I or class II molecules of the MHC is
necessary for the stimulation of a cellular immune response. This report describes the …
necessary for the stimulation of a cellular immune response. This report describes the …
[HTML][HTML] Residual on column host cell protein analysis during lifetime studies of protein A chromatography
Capacity reduction in protein A affinity chromatography with extended cycling during
therapeutic antibody manufacture is well documented. Identification of which residual proteins …
therapeutic antibody manufacture is well documented. Identification of which residual proteins …
Solid-Phase Synthesis of Peptide Radiopharmaceuticals Using Fmoc-N-ε-(Hynic-Boc)−Lysine, a Technetium-Binding Amino Acid: Application to Tc-99m-Labeled …
WEP Greenland, K Howland, J Hardy… - Journal of medicinal …, 2003 - ACS Publications
Labeling of proteins with metallic radionuclides for use in radiopharmaceuticals involves
covalently attaching a bifunctional chelator. In principle, use of smaller peptides allows this …
covalently attaching a bifunctional chelator. In principle, use of smaller peptides allows this …
[HTML][HTML] Modification of bacterial microcompartments with target biomolecules via post-translational SpyTagging
Bacterial microcompartments (BMCs) are proteinaceous organelle-like structures formed
within bacteria, often encapsulating enzymes and cellular processes, in particular, allowing …
within bacteria, often encapsulating enzymes and cellular processes, in particular, allowing …
Human T cell responses to human papillomavirus type 16 L1 and E6 synthetic peptides: identification of T cell determinants, HLA-DR restriction and virus type …
…, GAJ McIndoe, K Howland… - Journal of General …, 1990 - microbiologyresearch.org
Four T cell determinants in the major capsid protein of human papillomavirus (HPV) type 16
LI and one in the E6 protein associated with cellular transformation were defined using …
LI and one in the E6 protein associated with cellular transformation were defined using …
Structural analysis of a peptide-HLA class II complex: identification of critical interactions for its formation and recognition by T cell receptor
An assay for the binding of peptides to major histocompatibility complex (MHC) class II proteins
on the surface of cells has been used to determine the relative importance of the amino …
on the surface of cells has been used to determine the relative importance of the amino …