The robo gene in Drosophila was identified in a large-scale mutant screen for genes that
control the decision by axons to cross the CNS midline. In robo mutants, too many axons cross …

Two tandem Netrin genes in Drosophila are expressed at the midline of the developing CNS
and in different subsets of neurons, muscles, and epidermal patches. In embryos carrying a …

We have identified a Drosophila member of the deleted in colorectal cancer (DCC) gene
family. The frazzled gene encodes transmembrane proteins that contain four immunoglobulin …

We describe the successful application of a modified gene-trap approach, the secretory trap,
to systematically analyze the functions in vivo of large numbers of genes encoding secreted …

Microscopy is an essential tool in a huge range of research areas. Until now, microscopy
has been largely restricted to imaging in the visible region of the electromagnetic spectrum. …

The search to understand the mechanisms regulating brain wiring has relied on biochemical
purification approaches in vertebrates and genetic approaches in invertebrates to identify …

Conventional cameras rely upon a pixelated sensor to provide spatial resolution. An alternative
approach replaces the sensor with a pixelated transmission mask encoded with a series …

The molecular mechanisms controlling the ability of motor axons to recognize their appropriate
muscle targets were dissected using Drosophila genetics to add or subtract Netrin A, …

Cell-cell signalling of semaphorin ligands through interaction with plexin receptors is important
for the homeostasis and morphogenesis of many tissues and is widely studied for its role …

The term synaesthesia has been applied to a range of different sensory-perceptual and
cognitive experiences, yet how these experiences are related to each other is not well …