Over the past decade, the Nomenclature Committee on Cell Death (NCCD) has formulated
guidelines for the definition and interpretation of cell death from morphological, biochemical, …

Autophagy is a core molecular pathway for the preservation of cellular and organismal
homeostasis. Pharmacological and genetic interventions impairing autophagy responses …

Inactivation of cell death is a major step in tumor development, and p53, a tumor suppressor
frequently mutated in cancer, is a critical mediator of cell death. While a role for p53 in …

Over the past two decades, the molecular machinery that underlies autophagic responses
has been characterized with ever increasing precision in multiple model organisms. Moreover…

Autophagy plays a key role in the maintenance of cellular homeostasis. In healthy cells,
such a homeostatic activity constitutes a robust barrier against malignant transformation. …

Although metabolic alterations have been observed in cancer for almost a century, only
recently have the mechanisms underlying these changes been identified and the importance of …

The tumour suppressor p53 inhibits cell growth through activation of cell-cycle arrest and
apoptosis 1 , and most cancers have either mutation within the p53 gene or defects in the …

Loss of the p53 tumor suppressor pathway contributes to the development of most human
cancers. p53 is a nuclear protein that functions as a regulator of transcription. Significant …

Maintenance of protein homeostasis and organelle integrity and function is critical for cellular
homeostasis and cell viability. Autophagy is the principal mechanism that mediates the …

This review captures the synthesis, assembly, properties, and applications of copper chalcogenide
NCs, which have achieved significant research interest in the last decade due to their …